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Naoto Shirasu; Shin'ichiro Yasunaga – Biochemistry and Molecular Biology Education, 2024
Here, we propose a laboratory exercise to quickly determine single nucleotide polymorphisms (SNPs) in human "alcohol dehydrogenase 1B (ADH1B)" and "aldehyde dehydrogenase 2 (ALDH2)" genes involved in alcohol metabolism. In this exercise, two different genotyping methods based on polymerase chain reaction (PCR), namely…
Descriptors: Genetics, Biochemistry, Students, Science Instruction
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Paige M. Russell; Jeffrey P. Potratz – Journal of Chemical Education, 2023
Three computer-based activities focusing on fundamentals of binding interactions are described that are powered by Desmos, freely available web-based software. The software allows the instructor to monitor the progress of each student completing the activity by privately viewing their answers in real time, to enforce class pacing by modulating…
Descriptors: Computer Software, Science Activities, Science Instruction, Computer Uses in Education
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Juan Carlos Vega-Garzón; Duverney Chaverra-Rodriguez – Biochemistry and Molecular Biology Education, 2025
The COVID-19 pandemic affected a large range of in-person education activities in Colombia. This created great limitations in academic performance for students with reduced access to communication technologies and deepened the educational gaps in the country. This was particularly true for sciences such as biochemistry. In Colombia, molecular…
Descriptors: Handicrafts, Molecular Structure, Biology, Science Instruction
Kylie Light; Jordan Brooks; Yun-Seok Choi – Journal of Chemical Education, 2023
Sanger sequencing, also known as dideoxy sequencing, is a widely used method for DNA sequencing, particularly for cloned plasmids and clinical samples. This technique requires a combination of essential biochemistry skills, such as a chain-termination reaction, gel electrophoresis, and fluorescence detection. Unfortunately, there is a lack of…
Descriptors: Genetics, Biochemistry, Science Instruction, Science Activities
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Clare G.-C. Franovic; Keenan Noyes; Jon R. Stoltzfus; Christina V. Schwarz; Tammy M. Long; Melanie M. Cooper – Journal of Chemical Education, 2023
There is emerging recognition that mechanistic reasoning about scientific phenomena as well as developing an interdisciplinary understanding of science are valuable for student success. Our team of chemistry, biology, and teacher education researchers strives to support students in their interdisciplinary learning and engage them in causal…
Descriptors: Undergraduate Students, Chemistry, Biology, Science Instruction
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Marisa Freitas; Carina Proenc¸a; Daniela Ribeiro; Maria Beatriz Quinaz-Garcia; Alberto N. Arau´jo; Eduarda Fernandes – Journal of Chemical Education, 2023
Enzymes, enzymatic kinetics, and enzyme inhibition are topics covered in undergraduate biochemistry textbooks, having perceptible relevance to everyday life. The experimental use of enzymes involved in basic physiologic processes may be of utmost pedagogic interest because they bring evidence on how a significant number of drugs are used to…
Descriptors: Biochemistry, Undergraduate Study, Laboratory Experiments, Science Instruction
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Kit Ying Rebecca Lee; Yat Nam Bernard Ng; Minghui Daisy Chen – Journal of Chemical Education, 2024
Metabolism is always a challenging topic in biochemistry. In our project, a courseware called "Metabolism Metro" was developed. "Metabolism Metro" is a self-learning tool which aims to facilitate students learning of metabolic pathways in an interactive and easy-to-understand manner. The courseware includes both pre-class and…
Descriptors: Courseware, Biochemistry, Metabolism, Science Education
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Keira D. Naff; Jeri L. Tyler; Dima H. Hamza; Jonathan D. White – Journal of Chemical Education, 2023
Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…
Descriptors: Genetics, Undergraduate Students, Undergraduate Study, College Science
Nicole Calma-Roddin; Kevin Park; Jacqueline Keighron – Journal of Chemical Education, 2023
The three-dimensional nature of macromolecules is often difficult for undergraduate students to grasp. This leads to difficulties in understanding key concepts in Biochemistry, such as protein function and conformational change. Virtual reality (VR) technologies, which can aid students in three-dimensional visualizations, have been shown to…
Descriptors: Technology Integration, Technology Uses in Education, Museums, Undergraduate Students
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Paola Go´mez Buitrago; Hendrys Tobar-Mun~oz; Danny Arteaga – Journal of Chemical Education, 2024
In response to the great challenge that the teaching of basic sciences currently entails in the new generations of young people and seeking to awaken the interest of our students in chemistry and its areas of influence, we developed an innovative card game named "Amino-structure" which served as a key tool to implement an active learning…
Descriptors: College Students, Biochemistry, Science Instruction, Engineering Education
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Ramos-de-la-Peña, Ana Mayela; Mercado-Valenzo, Oscar Mario; Clorio-Carrillo, Jorge Abraham; López-Incio, Jazmin Dessiret; Monroy-Borrego, Andrea Gabriela; Marrero-Bretado, Mariana Monserrat; González-Valdez, José; Aguilar, Oscar – Biochemistry and Molecular Biology Education, 2021
A laboratory exercise for undergraduate advanced students of enzymology and biocatalysis is presented. Since enzyme assays can be quenched or continuous, this experiment compares the performance of two quenching agents for lactase, in a continuous setup. Enzymatic activity of [beta]-galactosidase ("Aspergillus oryzae") was determined…
Descriptors: Science Activities, Undergraduate Students, Advanced Courses, College Science
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Melanie B. Berkmen; Melisa Balla; Mikayla T. Cavanaugh; Isabel N. Smith; Misael Eduardo Flores-Artica; Abby M. Thornhill; Julia C. Lockart; Celeste N. Peterson – Biochemistry and Molecular Biology Education, 2025
Biochemistry and molecular biology students are asked to understand and analyze the structures of small molecules and complex three-dimensional (3D) macromolecules. However, most tools to help students learn molecular visualization skills are limited to two-dimensional (2D) images on screens and in textbooks. The virtual reality (VR) App Nanome,…
Descriptors: Technology Uses in Education, Computer Simulation, Computer Oriented Programs, Science Instruction
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Rachel C. Branco; Holly V. Goodson; Erin M. Jonasson – Journal of Chemical Education, 2022
Case studies are helpful teaching tools that can bring scientific concepts to life. Here, we present a case study related to protein-ligand interactions, amino acids, protein structure, and protein modification. While protein-ligand interaction is a foundational concept within Biochemistry, there are few available case studies that focus on this…
Descriptors: Biochemistry, Science Instruction, Chemistry, Alzheimers Disease
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Palmquist-Gomes, Paul; Pérez-Pomares, José María; Guadix, Juan Antonio – Biochemistry and Molecular Biology Education, 2021
A high variety of experimental model organisms have been used in developmental biology practical lectures. The work with developing embryos is crucial to make students aware of the multiple biological phenomena underlying normal animal embryogenesis and morphogenesis and represent a unique experimental platform to analyze the impact of molecular…
Descriptors: Biochemistry, Undergraduate Students, College Science, Embryology
Tyler A. Shaffer; Carlos U. Herrada; Avery M. Walker; Laura D. Casto-Boggess; Lisa A. Holland; Timothy R. Johnson; Megan E. Jones; Yousef S. Elshamy – Journal of Chemical Education, 2023
Electrophoresis is integral to analytical and biochemistry experiences in undergraduate education; however, fundamental principles of the method are often taught in upper-level laboratories through hands-on experiences. A laboratory activity is reported that teaches the concepts of electrophoretic mobility and electroosmotic flow. A single…
Descriptors: Chemistry, Science Instruction, Teaching Methods, Cost Effectiveness
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