NotesFAQContact Us
Collection
Advanced
Search Tips
Laws, Policies, & Programs
Assessments and Surveys
What Works Clearinghouse Rating
Showing 1 to 15 of 29 results Save | Export
Peer reviewed Peer reviewed
Direct linkDirect link
Naoto Shirasu; Shin'ichiro Yasunaga – Biochemistry and Molecular Biology Education, 2024
Here, we propose a laboratory exercise to quickly determine single nucleotide polymorphisms (SNPs) in human "alcohol dehydrogenase 1B (ADH1B)" and "aldehyde dehydrogenase 2 (ALDH2)" genes involved in alcohol metabolism. In this exercise, two different genotyping methods based on polymerase chain reaction (PCR), namely…
Descriptors: Genetics, Biochemistry, Students, Science Instruction
Peer reviewed Peer reviewed
Direct linkDirect link
Keira D. Naff; Jeri L. Tyler; Dima H. Hamza; Jonathan D. White – Journal of Chemical Education, 2023
Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…
Descriptors: Genetics, Undergraduate Students, Undergraduate Study, College Science
Peer reviewed Peer reviewed
Direct linkDirect link
Ramos-de-la-Peña, Ana Mayela; Mercado-Valenzo, Oscar Mario; Clorio-Carrillo, Jorge Abraham; López-Incio, Jazmin Dessiret; Monroy-Borrego, Andrea Gabriela; Marrero-Bretado, Mariana Monserrat; González-Valdez, José; Aguilar, Oscar – Biochemistry and Molecular Biology Education, 2021
A laboratory exercise for undergraduate advanced students of enzymology and biocatalysis is presented. Since enzyme assays can be quenched or continuous, this experiment compares the performance of two quenching agents for lactase, in a continuous setup. Enzymatic activity of [beta]-galactosidase ("Aspergillus oryzae") was determined…
Descriptors: Science Activities, Undergraduate Students, Advanced Courses, College Science
Peer reviewed Peer reviewed
Direct linkDirect link
Palmquist-Gomes, Paul; Pérez-Pomares, José María; Guadix, Juan Antonio – Biochemistry and Molecular Biology Education, 2021
A high variety of experimental model organisms have been used in developmental biology practical lectures. The work with developing embryos is crucial to make students aware of the multiple biological phenomena underlying normal animal embryogenesis and morphogenesis and represent a unique experimental platform to analyze the impact of molecular…
Descriptors: Biochemistry, Undergraduate Students, College Science, Embryology
Peer reviewed Peer reviewed
Direct linkDirect link
Park, Junyun; Obeng, Jeremiah; Spezia, Peter; Huang, Jonathan; Morrone, Dana J. – Biochemistry and Molecular Biology Education, 2021
Student feedback from an undergraduate biochemistry lab course suggested the use of visibly traceable proteins may assist learning. Based on this feedback, we used guided inquiry lab exercises where students developed and characterized a suite of fluorescent protein-dihydrofolate reductase (DHFR) fusions as tools for a biochemistry teaching lab.…
Descriptors: Biochemistry, Science Instruction, College Science, Undergraduate Study
Peer reviewed Peer reviewed
Direct linkDirect link
Stewart, John F.; Gustafson, John E.; Moore, Michael E.; Forshee, J. Lance; Canaan, Patricia; French, Donald P. – American Biology Teacher, 2023
Students who experience research as undergraduates tend to remain in science, technology, engineering, and mathematics fields. Since course-based undergraduate research experiences (CUREs) are often expensive to implement, we developed a relatively inexpensive first-semester research course for majors entitled "Freshman Research in…
Descriptors: College Freshmen, Majors (Students), Science Education, Cost Effectiveness
Peer reviewed Peer reviewed
Direct linkDirect link
Johnson, Josiah W.; Mitchell, Christian D.; Deloach, Anna M.; Simpson, Hannah E.; Dunlap, Tori B. – Journal of Chemical Education, 2019
Protein structure, function, and signaling are a large portion of biochemistry. Because of this, proteins are often used as model systems in biochemistry laboratory courses, where a course-long project might comprise protein expression, purification, and characterization. Two common protein expression methods are isopropyl…
Descriptors: Biochemistry, Science Laboratories, Science Instruction, Undergraduate Students
Peer reviewed Peer reviewed
Direct linkDirect link
Faraj, Santiago Enrique; Rossi, Rolando Carlos; Montes, Mónica Raquel – Journal of Biological Education, 2021
This report describes the implementation of a laboratory exercise for an advanced biochemistry or enzyme kinetics class at the undergraduate or graduate level, designed to improve understanding of protein conformational changes associated with the binding of a ligand. Students measure the fluorescence changes induced by the conformational…
Descriptors: College Science, Biochemistry, Science Instruction, Science Laboratories
Peer reviewed Peer reviewed
Direct linkDirect link
Rutter, Charles; Pancorbo, Jennifer – Chemical Engineering Education, 2020
Fermentation is responsible for the production of myriad products across a variety of industrial sectors. In particular, the biomanufacturing industry requires a labor force proficient in fermentation and its associated technologies to drive the production of recombinant protein therapeutics. This paper describes the development of a course that…
Descriptors: Biotechnology, Manufacturing Industry, Biochemistry, Scientific Concepts
Peer reviewed Peer reviewed
Direct linkDirect link
Sikora, Arthur; Irby, Stefan M.; Hall, Bonnie L.; Mills, Stephen A.; Koeppe, Julia R.; Pikaart, Michael J.; Wilner, Samantha E.; Craig, Paul A.; Roberts, Rebecca – Journal of Chemical Education, 2020
Campus shutdowns during the SARS-CoV-2 pandemic posed unique challenges to faculty and students engaged in laboratory courses. Formerly hands-on experiments had to be quickly pivoted to emergency remote learning. While some resources existed prior to this period, many currently available online modules and/or simulations focus on a single…
Descriptors: COVID-19, Pandemics, Distance Education, School Closing
Peer reviewed Peer reviewed
Direct linkDirect link
De Luca, Belén M.; Nudel, Clara B.; Gonzalez, Rodrigo H.; Nusblat, Alejandro D. – Biochemistry and Molecular Biology Education, 2017
Biocatalysis is a fundamental concept in biotechnology. The topic integrates knowledge of several disciplines; therefore, it was included in the course "design and optimization of biological systems" which is offered in the biochemistry curricula. We selected the ciliate tetrahymena as an example of a eukaryotic system with potential for…
Descriptors: Biotechnology, Biochemistry, Nutrition, Metabolism
Peer reviewed Peer reviewed
Direct linkDirect link
Siitonen, Vilja; Räty, Kaj; Metsä-Ketelä, Mikko – Biochemistry and Molecular Biology Education, 2016
The "'Streptomyces' genetics and secondary metabolism" laboratory course gives an introduction to the versatile soil dwelling Gram-positive bacteria "Streptomyces" and their secondary metabolism. The course combines genetic modification of "Streptomyces"; growing of the strain and protoplast preparation, plasmid…
Descriptors: Science Laboratories, Genetics, Metabolism, Introductory Courses
Peer reviewed Peer reviewed
Direct linkDirect link
Berndsen, Christopher E.; Young, Byron H.; McCormick, Quinlin J.; Enke, Raymond A. – Biochemistry and Molecular Biology Education, 2016
Single nucleotide polymorphisms (SNPs) in DNA can result in phenotypes where the biochemical basis may not be clear due to the lack of protein structures. With the growing number of modeling and simulation software available on the internet, students can now participate in determining how small changes in genetic information impact cellular…
Descriptors: Biochemistry, Genetics, Science Instruction, Sequential Approach
Peer reviewed Peer reviewed
Direct linkDirect link
Erasmus, Daniel J.; Brewer, Sharon E.; Cinel, Bruno – Biochemistry and Molecular Biology Education, 2015
Undergraduate laboratories expose students to a wide variety of topics and techniques in a limited amount of time. This can be a challenge and lead to less exposure to concepts and activities in bio-inorganic chemistry and analytical chemistry that are closely-related to biochemistry. To address this, we incorporated a new iron determination by…
Descriptors: Biochemistry, Inorganic Chemistry, Undergraduate Study, Science Laboratories
Peer reviewed Peer reviewed
Direct linkDirect link
Robinson, Rebekah L.; Neely, Amy E.; Mojadedi, Wais; Threatt, Katie N.; Davis, Nicole Y.; Weiland, Mitch H. – Biochemistry and Molecular Biology Education, 2017
The concepts of protein purification are often taught in undergraduate biology and biochemistry lectures and reinforced during laboratory exercises; however, very few reported activities allow students to directly gain experience using modern protein purification instruments, such as Fast Protein Liquid Chromatography (FPLC). This laboratory…
Descriptors: College Science, Active Learning, Chemistry, Science Laboratories
Previous Page | Next Page »
Pages: 1  |  2