A modified version "Tobacco Induced Mutations" of Ames assay experiment provides a meaningful context for students to learn about the concept of mutations by using a known carcinogen that is tobacco. This experiment shows toxicological concept of the dose/response relationship and visually demonstrates when a mutation have occurred in bacteria…

Describes experiments on diffusion of gases, volumetric approach to water of hydration, and toxicity of chemicals in the laboratory. Also describes an inexpensive automatic pipette, overhead projection of chemical reactions, and an alternative method for demonstrating flame tests. (JN)

Suggests that a governmental agency, most likely Occupational Safety and Health Administration (OSHA) be considered in the safety design stage of any experiment. Focusing on OSHA's role, discusses such topics as occupational health hazards of toxic chemicals in laboratories, occupational exposure to benzene, and role/regulations of other agencies.…

Describes a laboratory experiment in which Paramecium caudatum was used to demonstrate the toxic effect of cigarette smoke on the cilia of epithelium cells lining the trachea and bronchi of smokers. Provides background information and explains the procedure, including how to make a simple mechanical smoking device. (TW)