We describe a three-day advanced organic laboratory experience that includes the solid-phase synthesis of an unknown three amino acid polypeptide for junior/senior undergraduate chemistry majors. Students conduct a series of 1D and 2D NMR experiments (HSQC, HMBC, TOCSY) and analyze the data to identify the side chain residues of the peptide and…

Students sometimes learn about a model of the "scientific method" that is linear and clear cut. While this approach may have pedagogical advantages, it does not reflect how science is often done in practice. The Experimental Modeling Framework (EMF) describes the complex and iterative process of experimentation in the domain of physics,…

Despite the importance of asymmetric catalysis in both the pharmaceutical and commodity chemicals industries, asymmetric catalysis is under-represented in undergraduate chemistry laboratory curricula. A novel guided-inquiry experiment based on the asymmetric aldol addition was developed. Students conduct lab work to compare the effectiveness of…

We introduce a virtual physics laboratory, 'PhysLab', created using 3D video game technology suitable for advanced level physics courses in secondary schools. This comprises 32 simulated experiments covering a range of physics topics, selected in collaboration with practicing school teachers. PhysLab is made available at no cost for the physics…

Surface modification has been considered as a fundamental item in upper-division undergraduate and master courses. Thus, the development of experiments regarding processes and characterization of surface-modification phenomena is highly desired. In this article, we propose an electrochemical and computational study of widely used…

A laboratory experiment was developed to follow the gelation of a polyvinyl alcohol (PVA) solution upon addition of borax by using rotational viscometry. The rheological properties of the gel were examined, measuring the dependence of viscosity and shear stress on the shear rate. Time-dependent studies were also conducted in which the viscosity of…

Synthesis of quantum dots is a valuable experiment for demonstration and discussion of quantum phenomena in undergraduate chemistry curricula. Recently, a new class of all-inorganic perovskite quantum dots (QDs) with a formula of CsPbX[subscript 3] (X = Cl, Br, I) was presented and attracted tremendous attention. Here we adapt the synthesis of…

Many small-molecule antioxidants found in whole fruits and vegetables are analyzed and identified in this laboratory module for upper-division biochemistry courses. During this experiment, students develop their knowledge of the bioactivity of fruit and vegetable products while learning techniques to identify vitamins and nutritionally derived…

A new method for teaching advanced laboratories at the undergraduate level is presented. The intent of this approach is to get students more engaged in the lab experience and apply critical thinking skills to solve problems. The structure of the lab is problem-based and provides students with a research-like experience. Students read the current…

Tetrakis(4-sulfonatophenyl)porphyrin (TSPP) was immobilized on patterned paper and used as a sensor for heavy metal ions in an advanced organic chemistry course. The resulting sensor could detect Hg[superscript 2+] and Cd[superscript 2+] ions colorimetrically, while Cu[superscript 2+] ion resulted in fluorescence quenching, thus demonstrating a…

Efforts to reform undergraduate chemistry laboratory coursework typically focus on the curricula of introductory-level courses, while upper-level courses are bypassed. This study used video-stimulated recall to interview 17 junior- and senior- level chemistry majors after they carried out an experiment as part of a laboratory course. It is assumed…

Analytical method transfer (AMT) and dissolution testing are important topics required in industry that should be taught in analytical chemistry courses. Undergraduate students in senior level analytical chemistry laboratory courses at Kennesaw State University (KSU) and St. John Fisher College (SJFC) participated in development, validation, and…

In this paper, we describe a two-week learning module where students tested the role of the "fruitless" gene on aggression and courtship in "Drosophila melanogaster" via team-based learning (TBL) strategies. The purpose of this module was to determine if TBL could be used in the future as a platform to implement the course…

This three-week advanced-level organic experiment provides students with an inquiry-based approach focused on learning traditional skills such as primary literature interpretation, reaction design, flash column chromatography, and NMR analysis. Additionally, students address higher-order concepts such as the origin of azulene's blue color,…

A high-performance liquid chromatography experiment to determine the concentration of caffeine and vitamin B6 in sports energy drinks has been developed. This laboratory activity, which is appropriate for an upper-level instrumental analysis course, illustrates the standard addition method and simultaneous determination of two species. (Contains 1…