Here, we present a laboratory activity in which the students work on an analysis of a questioned document that was written with one out of five possible pens. As a forensics study, the activity applied chemistry and analytical chemistry tools to solve the case. The students were able to apply polarity and solubility concepts to select and discard…

A multioutcome, discovery-based column (CC) and thin layer chromatography (TLC) experiment has been designed for introductory organic chemistry. Multiple outcomes were established using commercially available two- and three-component analgesic medications based on acetaminophen, acetylsalicylic acid (aspirin), and ibuprofen. A series of 11…

Recently, smart sensing/actuation paper has attracted significant interest due to its potential usage as a sustainable component in future electronics, robotics, and intelligent sensing devices. In acknowledging the importance of this topic for the engagement of students at the university level in conjunction with Industrial Revolution 4.0, it is…

Enzymes, enzymatic kinetics, and enzyme inhibition are topics covered in undergraduate biochemistry textbooks, having perceptible relevance to everyday life. The experimental use of enzymes involved in basic physiologic processes may be of utmost pedagogic interest because they bring evidence on how a significant number of drugs are used to…

By hosting a college students' laboratory skills contest, we provide an interesting activity for students to cultivate good laboratory practices and thereby improve their laboratory skills. The substance of this contest is the detection of the hardness of water, which involves numerous laboratory skills such as solution preparation, weight by…

Nowadays, students have digital skills that are much larger than any other student in the past. Traditional experiments in a real laboratory are still fundamental, however an increasing number of computers can be used to simulate experiments close to the experimental environment. This can be seen as a great advantage for science learning, as…

Lateral flow assays play a key role in mass testing for COVID-19, for example, in schools. The red color of the detection lines is caused by gold nanoparticles that are conjugated to antibodies. Hence, these tests present a very topical learning opportunity in the emerging field of nanoscience. To highlight the role of gold nanoparticles, a…

In this laboratory experiment, students explore the aquatic photochemical fate of ranitidine and cimetidine, two common pharmaceutical pollutants found in wastewater. It provides an engaging environmental context for students to develop knowledge of reaction kinetics and photochemistry as well as skill in using analytical instrumentation. This…

Changes in environmental conditions can have a profound impact on organismal processes. For aquatic organisms, changes in dissolved oxygen concentration can have major repercussions, notably for physiological processes that have high long-term energetic costs and are more likely to rely on aerobic metabolic pathways. Here we propose a simple…

An experiment for the synthesis of N-acyl derivatives of natural amino acids has been developed as part of the Distributed Drug Discovery (D3) program. Students use solid-phase synthesis techniques to complete a three-step, combinatorial synthesis of six products, which are analyzed using LC-MS and NMR spectroscopy. This protocol is suitable for…

In this teaching laboratory, the students are directed in an exercise that involves designing and performing an experiment to determine estrogen's role in regulating delayed implantation (diapause) in female rats. To encourage active participation by the students, a discussion question is provided before the laboratory exercise in which each…

A versatile and portable apparatus was developed to demonstrate exciting visual displays of catalytic phenomena that introduce basic concepts in catalysis, renewable energy, and chemical safety, in order to pique scientific curiosity in a variety of audiences including middle and high school students, undergraduate and graduate students, and the…

Learning how cave formations, such as dripstone, take shape can be a valuable pedagogical tool in chemistry and geochemistry. Grasping the underlying processes requires students to synthesize knowledge of several different topical areas. The activity presented here uses an innovative experiment to connect chemistry concepts with an interesting…

Practicing chemists use models, diagrams, symbols, and figures to represent phenomena which cannot be detected by the human senses. Although research suggests that these external representations (ERs) can also be used to address the challenges that students have in learning chemistry, it is not clear how instructors' use of ERs aligns with their…

Recently, there have been many calls for an increase in instruction on the nature of science (NOS) in schools (i.e. NRC, 1996; NGSS Lead States, 2013). These calls recognize the importance of this topic at all levels of science education, but there is little guidance in terms of how to address it effectively in curricula. Similarly, there have…