The area of application of electrospray ionization mass spectrometry (ESI-MS), usually coupled with liquid chromatography, seems to be much larger than those of any other ionization method. It gives rise to the demand for new teaching methods that would effectively help students to master the principles of working with and making full use of the…

Paal--Knorr reactions are a classical method for synthesizing pyrroles, using 1,4-dicarbonyl compound and amine as reactants. It has the characteristics of green chemistry, as only two molecules of water are lost. In this teaching and learning experiment, 2,5-hexanedione and 4-"tert"-butylaniline were used to synthesize…

In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, chemical engineering, and pharmacy to various depths. Despite the significance of this phenomenon in pharmaceutical compounding…

Potash, an essential raw material of the 18th century, used to be produced from the ashes of plants. Known since antiquity, it was in 1807 that Humphry Davy put an end to the decades-long controversy about its nature as a compound. The technology behind potash production was implemented in Brazil by the Portuguese naturalist Frei Velloso. The…

As a model study for improving undergraduate organic chemistry laboratories with contemporary research concepts and practices, we evaluated a project module aiming at the synthesis of two porphyrin compounds. The module was implemented in a format that differed in several ways from that of a traditional course. It was designed for small student…

Background: Physics textbooks are a learning resource for students to acquire knowledge and information. The findings of previous studies on physics textbooks analysis have mostly focused on representations of gender, the nature of science, and scientific literacy. This study, therefore, extends the critical content analysis of physics textbooks…

This study addresses the measurement of high school students' epistemic knowledge associated with scientific experimentation (EKSE) which concerns "how" scientific experimentation generates knowledge and "why" that knowledge is justified. Based on philosophical, educational standards, and literature analyses, an EKSE construct…

The climate emergency is a source of anxiety for many young people. Images of drought, heat waves, wildfires, storms and flooding are increasingly appearing in the media. Today's children stand to be the recipients of our legacy of climate change, while not feeling empowered to do anything about it, so perhaps it is no wonder they are anxious.…

In science class, students learn by making and living information, enabling them to make sense of knowledge effectively and permanently and to associate it with daily life. Applied science courses make learning more qualified. While science teaching is carried out in application areas such as laboratories, virtual laboratories are used with the…

The concept of co-amorphous systems is introduced in an integrated laboratory experiment, designed for advanced chemistry students, using solvent-free, environmentally friendly mechanochemistry. The dual-drug naproxen-cimetidine co-amorphous system (NPX-CIM) is investigated as an example of the emergent field of medicinal mechanochemistry.…

As part of the current UK GCSE science curriculum, pupils need to use their understanding of science to answer questions about a series of core experiments. Problem-solving and applying knowledge to new situations is fundamental in enabling students to progress in science; however, many learners struggle to develop these skills. This can lead to…

We have developed a new foundation-level course at our institution that links the concept of chemical equilibria from four of the traditional subdisciplines (analytical, biochemistry, inorganic, and physical). The course, entitled Solution and Solid State Chemistry (CHEM 210), is designed to serve our chemistry and biochemistry majors, as well as…

Comprehensive curricula are described for middle and high school classrooms built around the synthesis of biodegradable calcium alginate capsules prepared from food-safe chemicals. Experiments and activities question whether calcium alginate capsules are a viable alternative to single-use water bottles and consider what characteristics are…

Curriculum-based undergraduate research experiences (CUREs) have been shown to increase student retention in STEM fields and are starting to become more widely adopted in chemistry curricula. Here we describe a 10-week CURE that is suitable for a second-semester organic chemistry laboratory course. Students synthesize small molecules and use…

A pilot study, funded by the Gatsby Charitable Foundation, supported 10 secondary schools across England to plan and deliver open-ended investigative practical work within science curriculum time. This enabled all students to experience the benefits of investigative work, rather than just those attending extracurricular STEM enrichment activities.…