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Direct linkHoffman, Janlyn R.; Brandwein, Nathan J.; Nguyen, Peter V. – Learning & Memory, 2019
Beta-adrenergic receptors ([beta]-ARs) prime hippocampal synapses to stabilize long-term potentiation (LTP). This "metaplasticity" can persist for 1-2 h after pharmacologic activation of [beta]-ARs. It requires activation of PKA (cAMP-dependent protein kinase) during [beta]-AR priming. A-kinase anchoring proteins (AKAPs) tether PKA to…
Descriptors: Animals, Science Experiments, Foreign Countries, Stimulation
Yun, Sung H.; Lee, Deok S.; Lee, Hyunjung; Baeg, Eun H.; Kim, Yun B.; Jung, Min W. – Learning & Memory, 2007
To obtain evidence linking long-term potentiation (LTP) and memory, we examined whether LTP induction modifies functional relationship among neurons in the rat hippocampus. In contrast to neurons in low-frequency stimulated or AP5-treated slices, LTP induction altered "functional connectivity," as defined by the degree of synchronous firing, among…
Descriptors: Long Term Memory, Mnemonics, Perceptual Motor Coordination, Stimulation
Campolattaro, Matthew M.; Halverson, Hunter E.; Freeman, John H. – Learning & Memory, 2007
The neural pathways that convey conditioned stimulus (CS) information to the cerebellum during eyeblink conditioning have not been fully delineated. It is well established that pontine mossy fiber inputs to the cerebellum convey CS-related stimulation for different sensory modalities (e.g., auditory, visual, tactile). Less is known about the…
Descriptors: Conditioning, Stimulation, Eye Movements, Auditory Stimuli
Cleary, Leonard J.; Byrne, John H.; Antzoulatos, Evangelos G.; Wainwright, Marcy L. – Learning & Memory, 2006
Repetitive, unilateral stimulation of "Aplysia" induces long-term sensitization (LTS) of ipsilaterally elicited siphon-withdrawal responses. Whereas some morphological effects of training appear only on ipsilateral sensory neurons, others appear bilaterally. We tested the possibility that contralateral morphological modifications may have…
Descriptors: Stimulation, Long Term Memory, Science Experiments, Scientific Methodology
Bristol, Adam S.; Carew, Thomas J. – Learning & Memory, 2005
Many studies of the neural mechanisms of learning have focused on habituation, a simple form of learning in which a response decrements with repeated stimulation. In the siphon-elicited siphon withdrawal reflex (S-SWR) of the marine mollusk "Aplysia," the prevailing view is that homosynaptic depression of primary sensory afferents underlies…
Descriptors: Stimulation, Inhibition, Habituation, Depression (Psychology)
United Nations Educational, Scientific, and Cultural Organization, Paris (France). – 1981
This collection of articles, originally published in national and international journals, is fifth in a series devoted to trends in teaching chemistry. The volume is divided into nine sections, each with an introduction explaining why papers have been selected and outlining their particular interest. Section I provides a list of atomic masses,…
Descriptors: Chemical Industry, Chemistry, College Science, Educational Games
