Proteins are essential for cell function, and their biological performance depends on three-dimensional (3D) structures. Insulin is made up of 51 amino acids and is a critical hormone involved in glycaemia regulation. In basic education, concepts involving proteins (synthesis, structure, interactions, and function) are abstract and difficult for…

Modeling is an important tool in science teaching and learning. Constructing a model instead of replicating one is more meaningful and better supports student learning than analyzing premade models (Firooznia 2015; Gouvea and Passmore 2017; Takemura and Kurabayashi 2014). Models include physical replications of a scientific phenomenon or analyzing…

Genetics is known to be one of the most challenging subjects in biology education because of its abstract concepts and processes. Therefore, hands-on experiments in authentic learning environments are supposed to increase comprehensibility and provide otherwise unavailable experiences to students. We applied a hands-on module in an out-of-school…

Most undergraduate students do not have practical experience working with model organisms despite having theoretical knowledge of their importance. This practical was developed to offer students experience working with three species of nematode, including "Caenorhabditis elegans." In the first task, students prepare slides of three…

Background: Spatial ability has an important place in science education, which is effective in raising future scientists. Although not in large numbers, studies show that teachers' spatial abilities somehow affect their teaching practices in the classroom and thus the spatial abilities of their students. Purpose: This study aimed to investigate…

The integration of scientific modeling into science teaching is key to the development of students' understanding of complex scientific phenomena, such as genetics. With this in mind, we conducted an introductory hands-on module during an outreach gene technology laboratory on the structure of DNA. Our module examined the influence of two model…

This study aimed at designing instructional material named Biotechnology Instruction Module (BIM) which is enriched with active learning methods to enhance the 8th grade students' learning of the topic. The development of the teaching materials proceeded within the stages of the ADDIE instructional design model. The final form of the instructional…

Undergraduate genetics courses have historically focused on simple genetic models, rather than taking a more multifactorial approach where students explore how traits are influenced by a combination of genes, the environment, and gene-by-environment interactions. While a focus on simple genetic models can provide straightforward examples to…

We examined the sophistication of middle school students' mechanistic explanations of genetics phenomena and how they interact with a technology-based explanation tool as they articulate and organize their ideas about the phenomena. We coordinated curriculum and assessment design frameworks to develop a middle school curriculum unit that engages…

A set of core ideas in the life sciences revolve around genetics, variation, and inheritance. While the "Next Generation Science Standards" (NGSS; NGSS Lead States 2013) emphasize teaching and learning about these concepts across K-12 grades, it is critical for early learners to begin to develop understanding of them. By the end of fifth…

The use of modeling-based instruction is very effective when learning science content in multiple disciplines for native speakers. However, the benefits of using this pedagogy with students learning English as a second language or English Learners (ELs) have not been widespread, especially at the upper secondary level. This article discusses the…

The CRISPR/Cas9 system is a powerful tool for gene editing and it has become increasingly important for biology students to understand this emerging technique. Most CRISPR laboratory teaching modules use complex metazoan systems or mammalian cell culture which can be expensive. Here, we present a lab module that engages students in learning the…

The high degree of complexity of macromolecular structure is extremely difficult for students to process. Students struggle to translate the simplified two-dimensional representations commonly used in biochemistry instruction to three-dimensional aspects crucial in understanding structure-property relationships. We designed four different physical…

Learning about chromosomes is standard fare in biology classrooms today. However, students may find it difficult to understand the relationships among the "genome", "chromosomes", "genes", a "gene locus", and "alleles". In the simple activity described in this article, which follows the 5E approach…

Model-based instruction offers numerous benefits to students, including increased content knowledge and critical thinking. This study explored the differences in the knowledge outcomes and reasoning processes employed by undergraduate students in an introductory biology lab as they constructed, revised, and simulated a computational model of a…