A laboratory experiment has been designed for teaching laboratories aimed at training students in the basics of spectroscopy in junior and senior level undergraduate chemistry courses. Despite the ubiquity of light-based tools in modern science, students often find it difficult to comprehend light and light-matter interactions. A portable…

Using crystal structure data, site directed mutagenesis, and real-time kinetic assays, students designed, expressed, and purified engineered mutants of human insulin-degrading enzyme (IDE). Students designed their own IDE mutants following "in silico" analysis, used inverse PCR to generate mutant plasmid expression constructs, expressed…

The area of application of electrospray ionization mass spectrometry (ESI-MS), usually coupled with liquid chromatography, seems to be much larger than those of any other ionization method. It gives rise to the demand for new teaching methods that would effectively help students to master the principles of working with and making full use of the…

Catalysis and catalytic cycles are widely used in both research and industry. The addition of a catalysis experiment into the undergraduate laboratory curriculum is important and necessary training to expand student learning. Here, an experiment demonstrating iron-based tandem catalysis was developed and implemented in an organic chemistry course…

A chemistry laboratory experiment is described to introduce undergraduate college students to membrane separation technology. This experiment combines a simple nanowire membrane fabrication and visually indicated molecule separation. The membrane is produced via coprecipitation synthesis followed by a filtration assembly process, which can be…

Nanotechnology has been recognized as an important driver of the future economy, and so nanoscience is increasingly being incorporated into the undergraduate chemistry curriculum. This experiment includes the chemical synthesis, optical and chemical testing, and microscopic imaging of gold nanoparticles. Since nanoparticles are too small to…

Surface chemistry impacts technology, advancing the development of new heterogeneous catalysts, semiconductor devices, and materials synthesis. Carbon surfaces are ubiquitous in various fields, and the surface reactivity can be altered by surface functionalization on the molecular scale, introducing functional groups, thus shifting their…

Given the importance of self-healing polymers for chemistry education, herein, we introduce our latest research results in self-healing materials based on thioctic acid into undergraduate chemistry laboratory. In this experiment, a natural small molecule, thioctic acid (TA), and a few other commercially-available reagents have been used to make a…

We present the use of an oxygen tolerant controlled radical polymerization (photoinduced electron/energy transfer-reversible addition fragmentation chain transfer polymerization, PET-RAFT) as a simple method for preparing controlled radical polymers in an undergraduate laboratory. Unlike conventional techniques, PET-RAFT polymerizations require no…

Single-molecule localization microscopy (SMLM) has revolutionized our ability to visualize cellular structures, offering unprecedented detail. However, the intricate biophysical principles that underlie SMLM can be daunting for newcomers, particularly undergraduate and graduate students. To address this challenge, we introduce the fundamental…

We have developed a guided-inquiry laboratory exercise in which students perform viscosity measurements to infer the structure of poly(vinyl alcohol) (PVA) in aqueous solution. The activity combines both experiments and modeling. In the experimental portion of the exercise, students measure the viscosity of several solutions of PVA with differing…

The prompt introduction of single-molecule science into undergraduates' curricula is an urgent but challenging task. However, the research experiments are often too complicated and the instruments are too expensive to be widely transferred into a compulsory course of undergraduate students. Herein, we introduce a recently developed nanopore…

The laboratory practice "Primary culture and directional differentiation of rat bone marrow mesenchymal stem cells (BMSCs)" is part of a required course for sophomore medical students at Tongji university, which has been conducted since 2012. Blended learning has been widely applied in medical courses. Based on a student-centered…

The concept of equilibrium vapor pressure plays a key role in the general chemistry curriculum; it is among the first and most easily demonstrated examples of equilibrium and frequently caps off the first semester of general chemistry where it illustrates the properties of liquids and intermolecular forces. We report here simple modifications of…

According to the definition, surface tension could be affected not only by intermolecular interaction but also by molecular area. However, in chemistry textbooks, surface tension is mainly explained only in terms of intermolecular interaction. Although the existing surface tension concept in the textbooks can lead to a variety of counterexamples,…