We describe a three-day advanced organic laboratory experience that includes the solid-phase synthesis of an unknown three amino acid polypeptide for junior/senior undergraduate chemistry majors. Students conduct a series of 1D and 2D NMR experiments (HSQC, HMBC, TOCSY) and analyze the data to identify the side chain residues of the peptide and…

The rapid transition to remote teaching in the spring of 2020 posed particular challenges for laboratory courses, which often involve students working hands-on with equipment in collaborative environments. Replicating in-person experiments was especially challenging for advanced lab courses that utilize specialized apparatus, which could not be…

This sequence of labs was developed for an upper level undergraduate cell biology course at Fairfield University. The labs are based on the use of the K562 human erythroleukemia cell line, a model system that is exceptionally amenable to an undergraduate cell biology lab course due to its ease of maintenance and propagation and usefulness for…

In a two-step synthesis starting with Ni(CH[subscript 3]COO)[subscript 2] ·4H[subscript 2]O and salicylaldehyde, students prepare Nethyl and N-isopropyl Ni(II) Schiff base (imine) complexes. After isolation and recrystallization, the products are characterized by room-temperature magnetic susceptibility measurements, FTIR spectroscopy, and…

A laboratory exercise for undergraduate advanced students of enzymology and biocatalysis is presented. Since enzyme assays can be quenched or continuous, this experiment compares the performance of two quenching agents for lactase, in a continuous setup. Enzymatic activity of [beta]-galactosidase ("Aspergillus oryzae") was determined…

Response to the continuing call to integrate scientific inquiry activities into high school education has taken different forms varying in student ownership, physical setting, time span, and mentoring resources. Important issues are how students perceive central dimensions of their experience, and the extent to which the inquiry framework design…

The Poisson distribution describes the probability of a certain number of events occurring in an interval of time when the occurrence of the individual events is independent of one another and the events occur with a fixed mean rate. Probably the best-known example of the Poisson distribution in the physics curriculum is the temporal distribution…

Students sometimes learn about a model of the "scientific method" that is linear and clear cut. While this approach may have pedagogical advantages, it does not reflect how science is often done in practice. The Experimental Modeling Framework (EMF) describes the complex and iterative process of experimentation in the domain of physics,…

Recently, interest in understanding the prospects of virtual environments, specifically virtual reality laboratories (VR Lab) -- those that involve a first-person practica experience via a desktop computer or head-mounted display -- in science education has increased. Seemingly ingrained in the process of implementing a VR Lab is a supposition of…

Despite the importance of asymmetric catalysis in both the pharmaceutical and commodity chemicals industries, asymmetric catalysis is under-represented in undergraduate chemistry laboratory curricula. A novel guided-inquiry experiment based on the asymmetric aldol addition was developed. Students conduct lab work to compare the effectiveness of…

The study of ruthenium polypyridyl complexes can be widely applied across disciplines in the undergraduate curriculum. Ruthenium photochemistry has advanced many fields including dye-sensitized solar cells, photoredox catalysis, lightdriven water oxidation, and biological electron transfer. Equally promising are ruthenium polypyridyl complexes…

This report describes the implementation of a laboratory exercise for an advanced biochemistry or enzyme kinetics class at the undergraduate or graduate level, designed to improve understanding of protein conformational changes associated with the binding of a ligand. Students measure the fluorescence changes induced by the conformational…

We describe a paper-based microfluidic device for iron(III) assay in an applied instrumental analysis laboratory. Simple and convenient devices were fabricated by the students using patterning of filter paper to investigate three different procedures: drawing a boundary with eyeliner or wax pen; drawing a boundary with waterproof permanent marker…

We introduce a virtual physics laboratory, 'PhysLab', created using 3D video game technology suitable for advanced level physics courses in secondary schools. This comprises 32 simulated experiments covering a range of physics topics, selected in collaboration with practicing school teachers. PhysLab is made available at no cost for the physics…

A laboratory experiment was developed to follow the gelation of a polyvinyl alcohol (PVA) solution upon addition of borax by using rotational viscometry. The rheological properties of the gel were examined, measuring the dependence of viscosity and shear stress on the shear rate. Time-dependent studies were also conducted in which the viscosity of…