The concept of co-amorphous systems is introduced in an integrated laboratory experiment, designed for advanced chemistry students, using solvent-free, environmentally friendly mechanochemistry. The dual-drug naproxen-cimetidine co-amorphous system (NPX-CIM) is investigated as an example of the emergent field of medicinal mechanochemistry.…

We have developed a new foundation-level course at our institution that links the concept of chemical equilibria from four of the traditional subdisciplines (analytical, biochemistry, inorganic, and physical). The course, entitled Solution and Solid State Chemistry (CHEM 210), is designed to serve our chemistry and biochemistry majors, as well as…

A method for using electronic structure calculations to predict the standard molar enthalpy of combustion for hydrocarbons is presented. In this approach, simple geometry optimizations can be used to accurately compute the enthalpy of combustion within 3% of the experimental value using Hartree-Fock, MP2, or virtually any functional in density…

In an idealized General Chemistry Laboratory curriculum, students would hone their experimental design ability with practice encouraged by laboratory exercises designed to be open-ended. However, traditional General Chemistry Laboratory courses often lack opportunities for students to design their own experiments, instead opting to provide…

This study investigates the challenge faced by eighth-grade students at Southern State Middle School in grasping abstract concepts within the domains of physical science, physics, and chemistry. This difficulty is manifested in their poor performance on summative assessments. A comprehensive analysis of state-provided data, in conjunction with…

Despite the recognized effectiveness of course-based undergraduate research experiences (CUREs), there are few examples of the development of a CURE-based course in a large-enrollment undergraduate organic chemistry laboratory. Herein, we describe the development and implementation of a series of undergraduate laboratory experiments centered…

Laboratory experimentation providing students with hands-on experiences can greatly enhance the teaching and learning of physics. However, traditional hands-on laboratories are very expensive, limiting the possibilities for practical activities. In addition, limited time for laboratory practices prevents teachers and students from conducting…

The topic of chemistry safety was included at the margins of traditional chemistry education in China. In order to understand the concerns of the safety issues based on the new chemistry curriculum in the mainland China secondary school, this study analyzed old and new secondary chemistry curriculum standards via the Natural Language Processing…

Recently, there have been many calls for an increase in instruction on the nature of science (NOS) in schools (i.e. NRC, 1996; NGSS Lead States, 2013). These calls recognize the importance of this topic at all levels of science education, but there is little guidance in terms of how to address it effectively in curricula. Similarly, there have…

Providing opportunities for science, technology, engineering, and mathematics undergraduates to engage in authentic scientific practices is likely to influence their view of science and may impact their decision to persist through graduation. Laboratory courses provide a natural place to introduce students to scientific practices, but existing…

A kinetic isotope effect (KIE) experiment is described for the physical chemistry laboratory. Students conduct a hypochlorite (household bleach) oxidation of an equimolar mixture of 1-phenylethanol and 1-deuterio-1-phenylethanol to acetophenone. The reaction occurs in a biphasic reaction mixture and follows first-order kinetics with respect to…

What follows is a description of the procedure for and results of a simple experiment on the formation of impact craters designed for the laboratory portions of lower mathematical-level general education science courses such as conceptual physics or descriptive astronomy. The experiment provides necessary experience with data collection and…

Although much of the scientific community concerns itself with ideas of a sustainable future, very little of this interest and motivation has reached the classroom experience of the average chemistry major, and therefore, it is imperative to expose students to these ideas early in their careers. The focus of most undergraduate chemistry curricula…

An instructional laboratory curriculum for a first-semester introductory organic chemistry course has been developed using microwave-assisted organic synthesis (MAOS). Taking advantage of short reaction times, materials were developed to facilitate collaborative experimental design, analysis, and debriefing of results during the normal laboratory…

Precipitation of barium phosphate from aqueous solutions of a barium salt and a phosphate salt forms the basis for a number of conclusions drawn in general chemistry. For example, the formation of a solid white precipitate is offered as evidence that barium phosphate is insoluble. Furthermore, analysis of the supernatant is used to illustrate the…