The substitution of carbonyl compounds with liquid bromine as a brominating agent is the most commonly employed synthesis method for a-bromoacetophenone and its derivatives. However, liquid bromine possesses certain drawbacks, such as volatilization, high toxicity, strong corrosion, and poor reaction selectivity, which limit its application and…

Active learning provides students with meaningful and introspective roles in education. However, active learning is difficult to achieve in online class settings, particularly for biology laboratories initially designed to offer direct interactions with live organisms. During the COVID-19 pandemic, a transition to online learning was required in…

We developed a curriculum for an upper-level molecular biology course-based undergraduate research laboratory class funded by a National Science Foundation CAREER grant that focuses on identifying new small proteins in the bacterium, "Escherichia coli." Our CURE class has been continually offered each semester for the last 10 years, with…

A gamified approach toward Viva voce was implemented in a postlab activity to evaluate students in teams. In a game-show manner, students in teams of three select from an array of anonymized options to reveal a random question. They then chose one member of the team to answer. The assessor evaluated the team by the side instead of facing the…

This study's general theme revolves around practical work in chemical education, and its scope is the employment of a novel inquiry strategy combined with a new openness level. We investigate how the controlled positive error, a new device for inquiry activities developed by us, affects undergraduate students' experience of an experiment and…

A set of inexpensive and pedagogically rich experiments focusing on S[subscript N]1, E1, and E2 reactions have been updated to include modern computational and spectroscopic analyses. The S[subscript N]1 experiment involves treatment of "tert"-amyl alcohol with hydrochloric acid to generate the corresponding alkyl chloride, which is used…

Lab courses are a significant component of biochemistry and molecular biology (BMB) education. In teaching the labs, we combine established techniques with novel approaches. Lab formats have also moved from traditional cookbook style labs to guided inquiry to course-based undergraduate research experiences (CUREs), where faculty bring their own…

In March, 2020, campus restrictions associated with COVID-19 necessitated significant changes to undergraduate instruction at institutions of higher education. Rapid, unplanned transitions to remote learning caused disruptions for all educators, especially those who traditionally facilitate student learning via wet labs or live animal…

Students are introduced to the concepts of static electricity at a school level and an under-graduate level. In this paper, we present an inexpensive and portable device that can be used to study the static electricity and verify polarity of the electric charge on materials in a triboelectric series. This device is developed at the Science…

Undergraduate laboratory courses, owing to their larger sizes and shorter time slots, are often conducted in highly structured modes. However, this approach is known to interfere with students' engagement in the experiments. To enhance students' engagement, we propose an alternative mode of running laboratory courses by creating some…

This study focuses on how the quality of students' arguments and their conceptions of data and evidence change as a result of experiencing two types of laboratory courses, one employing a scripted inquiry approach and the other employing argument-driven inquiry. The analysis explores the connections between students' conceptions of data and…

A classic undergraduate introductory experiment is to measure the diffraction and interference pattern from single and double slits to determine slit width and separation. Studies show that Course-based Undergraduate Research Experiences (CUREs) can make science more inclusive when offered at the undergraduate level. Additionally, CUREs help…

Living cells are crowded. The presence of so many macromolecules packed into a confined environment affects the structure and function of biological components, and the kinetics and thermodynamics of biochemical reactions. In fact, crowding studies have already led to important biological insights, such as the existence of metabolons and other…

In the world of higher education, one of the struggles instructors face in the classroom is engaging students in the material. A second discussion in higher education pedagogy is how to weigh content versus activity in the science classroom. How should college teaching be set up when students now have every fact ever found at their fingertips on a…

The real time PCR (qPCR) method provides a powerful method to assess levels of particular species of DNA. When combined with reverse transcription (RT-qPCR) it is the predominate technique to measure expression of gene transcripts. While this approach is very powerful, particular care must be taken in the design of the primers to facilitate…