Chemometric techniques such as partial least-squares (PLS) regression have been applied with huge success to a wide array of chemical problems including multicomponent analysis of analytes in complex mixtures. Despite this, there are few examples of laboratory pedagogical exercises that involve students in the acquisition of chemical data from…

In case-based learning, students develop and apply course knowledge to solve tangible and "real life" problems. This practice can enhance student motivation and engagement in the analytical laboratory. In this application of case-based learning students analyze commercially available oils for CBD content. In the state of Texas anyone can…

As an introduction to quadrupolar effects in NMR spectroscopy, students use low field ([superscript 1]H, 60 MHz), benchtop [superscript 13]C NMR spectroscopy to contrast the spin-spin coupling behavior of [superscript 13]C to the dipolar [superscript 1]H and quadrupolar [superscript 2]D in familiar solvents C(H/D)Cl[subscript 3], C(H/D)[subscript…

A laboratory experiment was designed to introduce the practical application of biocatalysis in Bachelor and Master courses in biotechnology and medicinal chemistry, respectively. To this aim, the lipase from "Candida rugosa" was characterized (protein concentration and activity), immobilized on a carrier (by hydrophobic adsorption), and…

Many of the current synthetic methodologies utilized within academic and industrial laboratories require knowledge of how to safely handle air- and moisture-sensitive reagents and work under inert atmospheres. As a result, the ACS Committee on Professional Training recommends incorporating synthetic methods that make use of these inert atmospheres…

A new project-based laboratory (PJBL) was developed for general chemistry students to tackle the steps involved in chemical water quality analysis using an accessible, real-world hydrologic system (the lakes of the Lower Grand Coulee, Washington). This PJBL was developed in a joint general chemistry and environmental geology course by a…

Regulation is a key concept for understanding the dynamics of metabolism in bacteria. This report outlines a simple laboratory experiment aimed at studying a key form of regulation in bacterial metabolism, exemplifying how microbes switch the flux of carbon towards alternative metabolic fates as a function of nutrient availability and according to…

General chemistry laboratories are a core requirement for nearly all STEM (Science, Technology, Engineering, and Mathematics) majors and have the greatest breadth in disciplines and audience of any STEM course at a university. A bioremediation Course-based Undergraduate Research Experience (CURE) for first-year undergraduate students was developed…

A laboratory experiment was developed for the continuous flow preparation of an aminal derived from the condensation of furfural with morpholine. The experiment introduces the students to concepts of green chemistry, heterogeneous catalysis, and continuous flow. A cheap and easy setup allows the heterogeneous catalyst reactor to be built in class.…

Course-based undergraduate research experiences (CUREs) integrate authentic research into undergraduate chemistry laboratories, introducing students to research while simultaneously reinforcing fundamental concepts. Despite their ubiquitous nature in bioanalytical research, few CUREs have been published applying the fundamental techniques of…

A multioutcome, guided inquiry-based liquid--liquid extraction (LLE) experiment has been designed for introductory organic chemistry. Multiple outcomes were established by identifying a series of red and blue dyes that are (1) soluble in organic solvent, (2) soluble in aqueous solution, or (3) soluble in either the organic or aqueous layers by…

A class of 18 students attending the last year of an Italian high school was divided into groups and performed the extraction of pigments contained in hibiscus tea. Each group worked at a different temperature and carried out multiple extractions using distilled water as a solvent. By means of UV-vis spectroscopy it was possible to determine the…

This paper introduces hands-on curricular modules integrated with research in atmospheric ice nucleation, which is an important phenomenon potentially influencing global climate change. The primary goal of this work is to promote meaningful laboratory exercises to enhance the competence of students in the fields of science, technology,…

Triboluminescence is a fascinating phenomenon that can engage students' interest in chemistry. However, safe, cost-effective, and accessible laboratory experiments featuring highly triboluminescent substances are limited. To bridge this gap, we present a simple, rapid, semimicro test tube preparation of the visually engaging manganese complex…

A Unit Operations Laboratory (UOL) is fundamental to undergraduate chemical engineering education. This article discusses a new course structure for the University of Kansas UOL and details for three new experiments covering the fundamentals of vapor-liquid equilibrium, fluid mechanics, and kinetics. Students apply knowledge from these courses as…