We describe a project implemented in the honors section of an upper-level analytical chemistry undergraduate course, in which students designed an experiment to compare the performance of two analytical techniques to determine the amount of ascorbic acid in a commercial sample. This project designed for 18 students is composed of three stages. In…

A new undergraduate organic laboratory experiment has been developed and implemented for the Ugi three-component synthesis of the topical anesthetic lidocaine with excellent atom economy. Paraformaldehyde, diethylamine, and 2,6-dimethylphenyl isocyanide were combined and conveniently stirred at room temperature for a week in methanol with acetic…

The Clemmensen reduction is a common example of a reaction demonstrating the deoxygenation of carbonyl groups, which is a topic that has been widely studied in the field of organic chemistry. The use of trimethylchlorosilane, as a substitute for concentrated hydrochloric acid, allows for the reduction of carbonyl groups. The Clemmensen reduction…

Green chemistry and chemical safety complement each other in reducing adverse health and safety outcomes. However, it is imperative to train students of advanced synthetic chemistry, beyond reaction mechanisms, to proactively connect complex experiments with hazard analysis, risk minimization, and planetary sustainability. Virtual experiments…

The Hofmeister series is a recurring trend that ranks ions' abilities to influence various aqueous processes in solution. Herein, a set of project-based experiments was developed for students in an upper-level physical chemistry laboratory to investigate the specific ion effects on the thermodynamics of caffeine partitioning between aqueous and…

The use of methanol-water mixtures as solvents for sample preparations is common in many instrumental analytical procedures for compound quantification at trace concentration levels. The reliability of the analytical method depends upon several factors including consistency of instrumental setup and calibration, quality of standards used and…

To enhance critical thinking and problem-solving skills, a project-based learning (PBL) approach for "Instrumental Techniques" courses in undergraduate physical chemistry was specifically developed for a pharmacy bachelor degree program. The starting point of this PBL was an open-ended question that is close to the student scientist's…

A thematic course called "Climate Change: Chemistry and Controversy" was developed for upper-level non-STEM students. This course used the socioscientific context of climate change to teach chemical principles and the nature of science. Students used principles of agnotology (direct study of misinformation) to debunk climate change…

In introductory laboratory courses, many universities are turning from traditional laboratories with predictable outcomes to inquiry-inspired, project-based laboratory curricula. In these labs, students are allowed to design at least some portion of their own experiment and interpret new, undiscovered data. We have redesigned the introductory…

A two-course sequence in electromagnetics (EM) was developed in order to address a perceived lack of student learning and engagement observed in a traditional, lecture-based EM course. The two-course sequence is named VECTOR: Vitalizing Electromagnetic Concepts To Obtain Relevance. This paper reports on the first course of the sequence. VECTOR…

The aim of the 2018 International Association for Development of the Information Society (IADIS) Cognition and Exploratory Learning in the Digital Age (CELDA) conference was to address the main issues concerned with evolving learning processes and supporting pedagogies and applications in the digital age. There have been advances in both cognitive…

Membrane transport is a fundamental concept that undergraduate students of cell biology understand better with laboratory experience. Formal teaching exercises commonly used to illustrate this concept are unbiological, qualitative, or intricate and time consuming to prepare. We have developed an exercise that uses uptake of radiolabeled nutrient…