Integrating agent-based models (ABMs) has been a popular approach for teaching emergent science concepts. However, students continue to find it difficult to explain the emergent process of natural selection. This study adopted an ontological framework--the Pattern, Agents, Interactions, Relations, and Causality (PAIR-C)--to guide the design of…

When students think of evolution, they might imagine T. rex, or perhaps an abiotic scene of sizzling electrical storms and harsh reducing atmospheres, an Earth that looks like a lunar landscape. Natural selection automatically elicits responses that include "survival of the fittest," and "descent with modification," and with…

In this article, we describe curricular materials developed to engage undergraduate students in evolutionary thinking around antibiotic resistance using the MEGA-plate experiment (Microbial Evolution and Growth Arena). This elegant and visual experiment, developed by the Kishony Lab, shows the development of antibiotic resistance on the timescale…

The present study has two main goals. First, it aims to examine the analogies an instructor uses about "DNA conservation across generations" in a university-level General Biology course. Second, it aims to examine the analogies used in those lessons according to Thiele and Treagust's framework. A qualitative case study design is adopted…

This research explored the impact of analogies and metaphors on the academic performance of senior school students in genetics within Ilorin, Nigeria. Three research questions and corresponding hypotheses were formulated and tested at a significance level of 0.05. A quasi-experimental design was used, involving 117 senior secondary school…

The purpose of this research was to determine the effect of the 5E model on the understanding of the molecular genetics concepts taught in general biology. The research had a quantitative focus and a quasi-experimental design, and the participants were 40 undergraduate students from a private university in the west of Puerto Rico, which were…

This study aimed to examine the impact of a context-based relating, experiencing, applying, cooperating, and transferring (REACT) strategy on the scientific reasoning (SR) abilities of tenth grade students. A mixed-method approach and convergent embedded experimental design were used. One hundred thirty-one students participated in the study in…

It is 157 years since Mendel presented his results on hybridisation in peas to the Brünn Society for Natural Science. The discipline of genetics has dramatically changed since then, with technological advancements revealing multifactorial causation and trait variability. Whilst none of this complexity featured in the discovery of classical…

In recent years, single-subject experimental courses have not been able to meet the demands of the comprehensive development of life sciences. This study is based on two fundamental disciplines, molecular biology and metabolomics, with the analysis and intervention of tumor-related genes as the starting point. A comprehensive experimental course…

Productive struggle is a process in which students expend effort to grapple with perplexing problems and make sense of something that is not immediately apparent and beyond their current level of understanding and capacity. The experience encourages students to reflect on and restructure their existing knowledge toward a new understanding of…

Analogies are used to make abstract topics meaningful and more easily comprehensible to learners. Incorporating simple analogies into STEM classrooms is a fairly common practice, but the analogies are typically generated and explained by the instructor for the learners. We hypothesize that challenging learners to create complex, extended analogies…

Students tend to think of their science courses as isolated and unrelated to each other, making it difficult for them to see connections across disciplines. In addition, many existing science assessments target rote memorization and algorithmic problem-solving skills. Here, we describe the development, implementation, and evaluation of an activity…

The ability of living organisms to respond and adapt to a changing climate is an urgent concern. However, current educational efforts aimed at increasing US undergraduate student climate literacy primarily focus on the causes of, and abiotic responses to, climate change, mostly neglecting the biotic impacts. Here, we present a new framework, the…

Due to its distinct phenotype and relatively simple inheritance pattern, the phenylthiocarbamide (PTC) loci is frequently utilized in teaching laboratories to demonstrate genetic concepts such as Mendelian inheritance and population genetics. We have developed a next-generation sequencing and bioinformatics approach to analyze the PTC gene locus…

Visual literacy, which is the ability to effectively identify, interpret, evaluate, use, and create images and visual media, is an important aspect of science literacy. As molecular processes are not directly observable, researchers and educators rely on visual representations (e.g., drawings) to communicate ideas in biology. How learners…