DNA-functionalized gold nanoparticles (DNA-AuNPs) have become a popular science theme since their invention in 1990s. They impact our daily lives by playing key roles in rapidly identifying and quantifying important analytes, and are a well-suited chemistry course content for beginners of chemical research. While the salt-aging method represents…

The helium-plasma (HePI) ionization mass spectrometry method was used to track the formation of reaction products and consumption of reactants by continually monitoring the vapors in the reaction headspace in real time. Two examples of the application procedure are presented here: a nucleophilic acyl substitution reaction and a 1,4-nucleophilic…

The discovery of ferrocene, Fe(C[subscript 5]H[subscript 5])[subscript 2], in the 1950s sparked the development of organometallic chemistry including metallocene compounds. Shortly after the isolation of ferrocene, the analogous ruthenium and osmium compounds were discovered. The preparation of ferrocene is common in undergraduate inorganic…

The diversity of scientific methods has received increasing attention in the field of science education. This paper aimed to investigate how preservice chemistry teachers perceive scientific methods and their diversity. Based on the theoretical framework of Brandon's Matrix and previous research, two tasks (i.e., Task 1 "understanding of the…

Quantitative analysis in analytical chemistry is divided into semi-,relative, and absolute analysis. An example of each analysis is pH test paper, internal standard, and standard addition, respectively. However, their definition and differences have not yet been explained to students sufficiently in classes as well as textbooks. Polymerase chain…

A 2 min film clip from the classic movie "Son of Frankenstein" is a surprisingly good illustration of, and introduction to, the scientific method as traditionally formulated. It may be useful in introducing the topic to a large variety of audiences. The text includes a description of the clip's content, questions to elicit student…

The diversity of scientific methods has received widespread recognition in recent years. The purpose of this review is to analyze the changes in the representation of laboratory work in Chinese senior high school chemistry textbooks in the past 30 years from the perspective of the diversity of scientific methods. This study was based on Brandon's…

Project-based learning is widely used in organic laboratories. This goal-oriented and inquiry-based learning model complements student-centered training. Such models focus on complicated issues or real-world problems on the frontier of chemistry. Students progress through three project phases: preproject, during the project, and postproject.…

Case studies are helpful teaching tools that can bring scientific concepts to life. Here, we present a case study related to protein-ligand interactions, amino acids, protein structure, and protein modification. While protein-ligand interaction is a foundational concept within Biochemistry, there are few available case studies that focus on this…

Since the appearance of the COVID-19 pandemic and its subsequent stage, the changes produced in the chemistry teaching process have allowed educators to use a wide range of strategies, methodologies, and tools to promote student learning. To carry out laboratory practices, some strategies reported include the use of simulators and educational…

While scientists place high value on the scientific method, its relevance to everyday life is often opaque to nonscientists. In undergraduate teaching, its implementation is primarily apportioned to upper-level, laboratory science classes for majors. Herein we describe the modification of a recipe as a real-world project for learning the…

Scientific success in the field of chemistry depends upon the mastery of a wide range of soft skills, most notably scientific writing and speaking. However, training for scientific communication is typically limited at the undergraduate level, where students struggle to express themselves in a clear and logical manner. The underlying issue is…

The Clemmensen reduction is a common example of a reaction demonstrating the deoxygenation of carbonyl groups, which is a topic that has been widely studied in the field of organic chemistry. The use of trimethylchlorosilane, as a substitute for concentrated hydrochloric acid, allows for the reduction of carbonyl groups. The Clemmensen reduction…

This article describes a laboratory course designed for nonmajors with a focus on food chemistry. The course can be delivered in a traditional format or in a fully remote, asynchronous format. The course is designed for students to develop an understanding of how chemists view the world and how chemists generate knowledge. Food chemistry was…

A significant challenge to the community of chemistry education is the creation of materials that can be used in nonscience settings, including those of social science and humanities classrooms. As part of a larger effort to engage new communities in understanding how science data can impact such settings, including in the community, an experiment…