This paper results from on-going reflection within the practitioners group "Plataforma de Interface à Ciência" (Platform of Professionals at the Interface of Science), an informal nationwide network in Portugal that brings together professionals involved in a large scope of activities related to research management, knowledge transfer and science communication. Due to the wide scope of functions and profiles of these professionals, they are not publicly nor institutionally recognised as part of the same professional group, which raises barriers for their recognition as relevant players in the research & innovation ecosystem and full achievement of their potential. We take stock of the several definitions of their roles found in the literature and conclude on the need for an inclusive approach to consider these roles as a profession. We propose the designation of Professionals at the Interface of Science (PIoS) to name this wide group of professionals that sits at the interface at all scientific disciplines.