This research seeks to describe the continuing predicament of R&D funding in the U.S. and to provide support for a return to higher R&D spending as a proportion of GDP to maintain American leadership in innovation. Historically, government investment has funded most foundational scientific research leading to technological advances in…

Translational research is a new and important way of thinking about research. It is a major priority of the National Institutes of Health (NIH) in the United States. NIH has created the Clinical and Translational Science Awards to promote this priority. NIH has defined T1 and T2 phases of translational research in the medical field, in order to…

Translational research originated in the medical field during the 1990s to describe taking discovery based research through the steps of applying it to clinical research and patient-oriented care. This model is implicitly linear, depicting the flow of information from researchers' bench, to a clinical trial bedside, to a primary care physician's…

Obtaining more federal funds is the expressed research goal in "Closing the Gaps by 2015." It states: By 2015, increase the level of federal science and engineering research and development obligations to Texas institutions to 6.5 percent of obligations to higher education institutions across the nation. In 2006, Texas institutions of…

This report critically examines studies of how scientific research drives innovation which is then translated into socio-economic benefits. It focuses on research evaluation insights that are relevant not only to the academic community, but also to policymakers and evaluation practitioners--and particularly to biomedical and health research…

Research on the structure, growth, development, and loss of hair in humans is reviewed. Studies designed to investigate methods of hair restoration using minoxidil and other compounds and treatments are discussed. (CW)

This report summarizes advances in the understanding of Alzheimer's disease, the major cause of mental disability among older Americans. The demography of the disease is discussed, noting that approximately 2.5 million American adults are afflicted with the disease and that the large increase in the number of Alzheimer's disease patients is due to…

Perspectives, policy issues, and options for Congressional action that relate most directly to the development and implementation of alternatives to animal use in research and testing are addressed in this report. Testimonies and reports include those from the Office of Technology Assessment, the National Institute of Health, and the Food and Drug…

This document provides an overview of the state of scientific study of Alzheimer's disease, a disease of catastrophic proportions whose symptoms include serious forgetfulness; changes in personality; confused, restless, and irritable behavior; and problems with judgment, concentration, writing, reading, speech, and naming of objects. It discusses…

Foresight analysis is proposed as an alternative to strategic planning in the scientific community, and its use by individual funding agencies to develop research resource allocation strategies for specific scientific fields is explored through an analysis in the field of cardiovascular research. Methodology is explained, and preliminary results…

In response to the President's Office of Science and Technology Policy request to identify promising areas for U.S. research investment in science and technology, this report contains briefings by outstanding researchers in several fields of science. This volume is the fifth in a series of briefings which are used to anticipate important new…

This report discusses the social and economic benefits of university research, arguing that if funding for research programs is reduced, short-term savings could impose long-term costs, depriving Americans of scientific breakthroughs, economic growth, and improvements in international competitiveness. It provides over 100 brief summaries of…