Semantic processing impairments are present in a proportion of individuals with autism spectrum disorder (ASD). Despite the numerous imaging studies investigating this language domain in ASD, there is a lack of consensus regarding the brain structures showing abnormal pattern of activity. This meta-analysis aimed to identify neural activation…

Background: Verbal fluency tasks are routinely used in clinical assessment and research studies of aphasia. People with aphasia produce fewer items in verbal fluency tasks. It remains unclear if their output is limited solely by their lexical difficulties and/or has a basis in their executive control abilities. Recent research has illustrated that…

In sentences such as "Some dogs are mammals," the literal semantic meaning ("Some 'and possibly all' dogs are mammals") conflicts with the pragmatic meaning ("'Not all' dogs are mammals," known as a "scalar implicature"). Prior work has shown that adults vary widely in the extent to which they adopt the…

The number of people diagnosed with Alzheimer's disease (AD), a progressive and terminal kind of dementia, continues to rise with an estimated 14 million Americans affected by 2050. Prior to an AD diagnosis, many individuals are diagnosed with mild cognitive impairment (MCI) and have similar, but less severe, symptoms as those with AD. A common…

Primary progressive aphasia (PPA) is a neurodegenerative condition characterized by language and cognitive decline. Word-retrieval deficits are the most common PPA symptom and contribute to impaired spoken expression. Intense semantic interventions show promise for improving word retrieval in people with PPA. In addition, people with PPA may learn…

In this dissertation, we present three empirical studies exploring the relationship between the central planning processes of spoken word production--lexical selection, phonological encoding, and phonetic encoding--and three other cognitive processes traditionally considered separate or peripheral to this core system. Study 1 examines the role of…

Background: Deafness has an adverse impact on children's ability to acquire spoken languages. Signed languages offer a more accessible input for deaf children, but because the vast majority are born to hearing parents who do not sign, their early exposure to sign language is limited. Deaf children as a whole are therefore at high risk of language…

In recent decades, a growing number of children have been diagnosed with autism spectrum disorder (ASD), a condition characterized by social interaction deficits and language impairment. Yet the precise nature of the disorder's impact on language development is not well understood, in part because of the language variability among children across…

The hypothesized role of Broca's area in sentence processing ranges from domain-general executive function to domain-specific computation that is specific to certain syntactic structures. We examined this issue by manipulating syntactic structure and conflict between syntactic and semantic cues in a sentence processing task. Functional…

The contribution of the left inferior prefrontal cortex in semantic processing has been widely investigated in the last decade. Converging evidence from functional imaging studies shows that this region is involved in the "executive" or "controlled" aspects of semantic processing. In this study, we report a single case study of a patient, PW, with…