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Direct linkSerdar Karatoprak; Sadettin Burak Acikel; Abdulbaki Akyildiz; Fatma Coskun; Fatma Hümeyra Yerlikaya – International Journal of Developmental Disabilities, 2024
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder, the etiology of which has not been clearly determined yet. There is increasing evidence that synaptic and dendritic changes are involved in the etiology of ASD. The aim of this study is to determine whether serum Thrombospondin-1 and Thrombospondin-2 differ between ASD…
Descriptors: Children, Autism Spectrum Disorders, Etiology, Metabolism
Masahiko Inoue; Yoichi Gomi; Soichiro Matsuda – International Journal of Developmental Disabilities, 2024
Introduction: Individuals with intellectual disabilities (ID) are at heightened risk of behavioral problems. Methods: This study investigated differences in the severity of challenging behaviors (CBs) among individuals with IDs at varying life stages. Data were collected from parents' retrospective interviews. Surveys were completed by 47 parents…
Descriptors: Foreign Countries, Intellectual Disability, Adults, Children
Saima, Sohei; Ihara, Hiroshi; Ogata, Hiroyuki; Gito, Masao; Murakami, Nobuyuki; Oto, Yuji; Ishii, Atsushi; Takahashi, Asami; Nagai, Toshiro – American Journal on Intellectual and Developmental Disabilities, 2022
The relationship between sensory processing and ASD-like and associated behaviors in patients with Prader-Willi Syndrome (PWS) remains relatively unexplored. Examining this relationship, 51 adults with PWS were administered the Pervasive Developmental Disorders Autism Society Japan Rating Scale (PARS), Short Sensory Profile (SSP-J), Food-Related…
Descriptors: Sensory Experience, Autism, Pervasive Developmental Disorders, Behavior Problems
Alison Fong; Robin Friedlander; Anamaria Richardson; Katie Allen; Qian Zhang – International Journal of Developmental Disabilities, 2024
Objective: This study aims to delineate the characteristics of severe self-injurious behaviors (SIB) in a cohort of children with autism and unspecified intellectual developmental disorder (UIDD) (intellectual disability) and examine potential risk factors for developing SIB. Methods: A retrospective chart review studied characteristics of severe…
Descriptors: Self Destructive Behavior, Children, Autism Spectrum Disorders, Developmental Disabilities
Major, Samantha; Isaev, Dmitry; Grapel, Jordan; Calnan, Todd; Tenenbaum, Elena; Carpenter, Kimberly; Franz, Lauren; Howard, Jill; Vermeer, Saritha; Sapiro, Guillermo; Murias, Michael; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2022
Prior eye-tracking studies involving autistic individuals have focused on total looking time or proportion of looking time to key regions of interest. These studies have not examined another important feature, the ability to sustain attention to stimuli. In particular, the ability to sustain attention to a dynamic social stimulus might reflect…
Descriptors: Eye Movements, Autism Spectrum Disorders, Attention, Visual Stimuli
Schwartzman, Jessica M.; Hardan, Antonio Y.; Gengoux, Grace W. – Autism: The International Journal of Research and Practice, 2021
Elevated parenting stress among parents of children with autism spectrum disorder is well-documented; however, there is limited information about variability in parenting stress and relationships with parent ratings of child functioning. The aim of this study was to explore profiles of parenting stress among 100 parents of young children with…
Descriptors: Autism, Pervasive Developmental Disorders, Stress Variables, Child Rearing
Charlot, Lauren R.; Weigle, Karen L.; Holingue, Calliope B. – Journal of Mental Health Research in Intellectual Disabilities, 2021
Introduction: Individuals with Down syndrome (DS) and IDD have lower psychiatric disorders rates than other individuals with IDD, and more information is needed about possible unique mental health needs of this group. Method: De-identified intake data for individuals with IDD, 101 with DS (mean age 27) and 4,366 without DS (mean age 25) served in…
Descriptors: Down Syndrome, Intellectual Disability, Mental Health, Physical Health
Taylor, Briana J.; Sanders, Kevin B.; Kyle, Marie; Pedersen, Kahsi A.; Veenstra-Vanderweele, Jeremy; Siegel, Matthew – Journal of Autism and Developmental Disorders, 2019
Psychiatric hospitalization of children with autism spectrum disorder (ASD) is common, but there is little comparative information available on different psychiatric hospital treatment models. Children with ASD ages 4-20 were enrolled upon admission to either a specialized (N = 53) or a general child psychiatric unit (N = 27). Caregivers completed…
Descriptors: Psychiatric Hospitals, Patients, Children, Adolescents
Chakraborty, Payal; Carpenter, Kimberly L. H.; Major, Samantha; Deaver, Megan; Vermeer, Saritha; Herold, Brianna; Franz, Lauren; Howard, Jill; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2021
Individuals with autism spectrum disorder are more likely than typically developing individuals to experience a range of gastrointestinal abnormalities, including chronic diarrhea, constipation, food sensitivities, and abdominal pain. These gastrointestinal symptoms have been associated with higher levels of irritability and aggressive behavior,…
Descriptors: Autism, Pervasive Developmental Disorders, Human Body, At Risk Persons
Mazurek, Micah O.; Lu, Frances; Macklin, Eric A.; Handen, Benjamin L. – Autism: The International Journal of Research and Practice, 2019
The newest edition of the "Diagnostic and Statistical Manual of Mental Disorders" (5th ed., DSM-5) introduced substantial changes to the diagnostic criteria for autism spectrum disorder, including new severity level ratings for social communication and restricted and repetitive behavior domains. The purpose of this study was to evaluate…
Descriptors: Severity (of Disability), Autism, Pervasive Developmental Disorders, Clinical Diagnosis
Sannar, Elise M.; Palka, Tamara; Beresford, Carol; Peura, Christine; Kaplan, Desmond; Verdi, Mary; Siegel, Matthew; Kaplan, Shir; Grados, Marco – Journal of Autism and Developmental Disorders, 2018
We examined the relationship between sleep duration and awakenings to Aberrant Behavior Checklist-Community (ABC-C) and Autism Diagnostic Observation Schedule (ADOS-2) scores in hospitalized youth with ASD and behavioral disturbance. Participants included 106 patients with a stay of at least 10 nights. Sleep in the hospital was recorded by staff…
Descriptors: Sleep, Correlation, Behavior Problems, Severity (of Disability)
Scahill, Lawrence; Aman, Michael G.; Lecavalier, Luc; Halladay, Alycia K.; Bishop, Somer L.; Bodfish, James W.; Grondhuis, Sabrina; Jones, Nancy; Horrigan, Joseph P.; Cook, Edwin H.; Handen, Benjamin L.; King, Bryan H.; Pearson, Deborah A.; McCracken, James T.; Sullivan, Katherine Anne; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2015
Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized…
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Problems, Repetition
White, Susan W.; Smith, Laura A.; Schry, Amie R. – Autism: The International Journal of Research and Practice, 2014
Assessment of global functioning is an important consideration in treatment outcome research; yet, there is little guidance on its evidence-based assessment for children with autism spectrum disorders. This study investigated the utility and validity of clinician-rated global functioning using the Developmental Disability-Child Global Assessment…
Descriptors: Autism, Pervasive Developmental Disorders, Measures (Individuals), Test Validity
Kent, Justine M.; Kushner, Stuart; Ning, Xiaoping; Karcher, Keith; Ness, Seth; Aman, Michael; Singh, Jaskaran; Hough, David – Journal of Autism and Developmental Disorders, 2013
Efficacy and safety of 2 risperidone doses were evaluated in children and adolescents with autism. Patients (N = 96; 5-17 years), received risperidone (low-dose: 0.125 mg/day [20 to <45 kg], 0.175 mg/day [>45 kg] or high-dose: 1.25 mg/day [20 to <45 kg], 1.75 mg/day [>45 kg]) or placebo. Mean baseline (range 27-29) to endpoint change…
Descriptors: Drug Therapy, Children, Adolescents, Autism
Viscidi, Emma W.; Johnson, Ashley L.; Spence, Sarah J.; Buka, Stephen L.; Morrow, Eric M.; Triche, Elizabeth W. – Autism: The International Journal of Research and Practice, 2014
Epilepsy is common in children with autism spectrum disorder (ASD) but little is known about how seizures impact the autism phenotype. The association between epilepsy and autism symptoms and associated maladaptive behaviors was examined in 2,645 children with ASD, of whom 139 had epilepsy, from the Simons Simplex Collection. Children with ASD and…
Descriptors: Symptoms (Individual Disorders), Autism, Pervasive Developmental Disorders, Epilepsy
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