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Carey, Meghan E.; Rando, Juliette; Melnyk, Stepan; James, S. Jill; Snyder, Nathaniel; Salafia, Carolyn; Croen, Lisa A.; Fallin, M. Daniele; Hertz-Picciotto, Irva; Volk, Heather; Newschaffer, Craig; Lyall, Kristen – Journal of Autism and Developmental Disorders, 2023
We examined associations between prenatal oxidative stress (OS) and child autism-related outcomes. Women with an autistic child were followed through a subsequent pregnancy and that younger sibling's childhood. Associations between glutathione (GSH), glutathione disulfide (GSSG), 8-oxo-deoxyguanine (8-OHdG), and nitrotyrosine and younger sibling…
Descriptors: Physiology, Prenatal Influences, Autism Spectrum Disorders, Pregnancy
Chien, Yi-Ling; Chen, Yu-Jen; Tseng, Wan-Ling; Hsu, Yung-Chin; Wu, Chi-Shin; Tseng, Wen-Yih Isaac; Gau, Susan Shur-Fen – Autism: The International Journal of Research and Practice, 2023
Whether altered white matter microstructural property of autistic people also exists in non-autistic siblings is uncertain. The microstructures of a neural tract may not be consistent throughout the whole track. We assessed 38 cognitive-able autistic males (aged 15.8 ± 4.4 years), 39 non-autistic siblings (16.5 ± 5.7 years), and 78 age- and…
Descriptors: Autism Spectrum Disorders, Siblings, Males, Adolescents
Jente Verbesselt; Jeroen Breckpot; Inge Zink; Ann Swillen – Journal of Speech, Language, and Hearing Research, 2024
Purpose: Individuals with proximal 16p11.2 copy number variants (CNVs), either deletions (16p11.2DS) or duplications (16p11.2Dup), are predisposed to neurodevelopmental difficulties and disorders, such as language disorders, intellectual disability, and autism spectrum disorder. The purpose of the current study was to characterize language…
Descriptors: Foreign Countries, Intelligence Tests, Vocabulary, Verbal Ability
DeVeney, Shari L.; Kyvelidou, Anastasia; Mather, Paris – Autism & Developmental Language Impairments, 2021
Background and Aims: The purpose of this exploratory study was to expand existing literature on prelinguistic vocalizations by reporting results of the first home-based longitudinal study examining a wide variety of behaviors and characteristics, including early vocalizations, across infants at low and elevated risk of autism spectrum disorder…
Descriptors: Autism Spectrum Disorders, Infants, Child Development, At Risk Persons
Schwichtenberg, AJ; Kellerman, Ashleigh M.; Young, Gregory S.; Miller, Meghan; Ozonoff, Sally – Autism: The International Journal of Research and Practice, 2019
Mother-infant interactions are a proximal process in early development and may be especially salient for children who are at risk for social difficulties (i.e. infant siblings of children with autism spectrum disorder). To inform how indices of maternal behaviors may improve parent-mediated interventions designed to mitigate autism spectrum…
Descriptors: Mothers, Infants, Parent Child Relationship, At Risk Persons
Bradshaw, Jessica; Trumbull, Ashley; Stapel-Wax, Jennifer; Gillespie, Scott; George, Nisha; Saulnier, Celine; Klaiman, Cheryl; Woods, Juliann; Call, Nathan; Klin, Ami; Wetherby, Amy – Autism: The International Journal of Research and Practice, 2020
Early intervention has been established as efficacious in addressing developmental delays in young children with autism spectrum disorder. Evidence that caregiver-implemented interventions are feasible and effective for young children with autism spectrum disorder is emerging, yet research suggests there are barriers to enrollment in clinical…
Descriptors: Autism, Pervasive Developmental Disorders, Infants, At Risk Persons