Recently, Bayesian diagnostic classification modeling has been becoming popular in health psychology, education, and sociology. Typically information criteria are used for model selection when researchers want to choose the best model among alternative models. In Bayesian estimation, posterior predictive checking is a flexible Bayesian model…

Popular item response theory (IRT) models are considered complex, mainly due to the inclusion of a random factor variable (latent variable). The random factor variable represents the incidental parameter problem since the number of parameters increases when including data of new persons. Therefore, IRT models require a specific estimation method…

Mediation analysis in Single Case Experimental Designs (SCEDs) evaluates intervention mechanisms for individuals. Despite recent methodological developments, no clear guidelines exist for maximizing power to detect the indirect effect in SCEDs. This study compares frequentist and Bayesian methods, determining (1) minimum required sample size to…

Bayesian methods to infer model dimensionality in factor analysis generally assume a lower triangular structure for the factor loadings matrix. Consequently, the ordering of the outcomes influences the results. Therefore, we propose a method to infer model dimensionality without imposing any prior restriction on the loadings matrix. Our approach…

Background: Traditionally, meta-analysis of time-to-event outcomes reports a single pooled hazard ratio assuming proportional hazards (PH). For health technology assessment evaluations, hazard ratios are frequently extrapolated across a lifetime horizon. However, when treatment effects vary over time, an assumption of PH is not always valid. The…

Within the frequentist structural equation modeling (SEM) framework, adjudicating model quality through measures of fit has been an active area of methodological research. Complicating this conversation is research revealing that a higher quality measurement portion of a SEM can result in poorer estimates of overall model fit than lower quality…

In this study, the accuracy of the artificial neural network (ANN) was assessed considering the uncertainties associated with the randomness of the data and the lack of learning. The Monte-Carlo algorithm was applied to simulate the randomness of the input variables and evaluate the output distribution. It has been shown that under certain…

This study proposes a Bayesian method for diagnostic classification models (DCMs) for a partially known Q-matrix setting between exploratory and confirmatory DCMs. This Q-matrix setting is practical and useful because test experts have pre-knowledge of the Q-matrix but cannot readily specify it completely. The proposed method employs priors for…

In psychology, researchers are often interested in testing hypotheses about mediation, such as testing the presence of a mediation effect of a treatment (e.g., intervention assignment) on an outcome via a mediator. An increasingly popular approach to testing hypotheses is the Bayesian testing approach with Bayes factors (BFs). Despite the growing…

Dynamic structural equation modeling (DSEM) is a useful technique for analyzing intensive longitudinal data. A challenge of applying DSEM is the missing data problem. The impact of missing data on DSEM, especially on widely applied DSEM such as the two-level vector autoregressive (VAR) cross-lagged models, however, is understudied. To fill the…

Model-Implied Instrumental Variable Two-Stage Least Squares (MIIV-2SLS) is a limited information, equation-by-equation, noniterative estimator for latent variable models. Associated with this estimator are equation-specific tests of model misspecification. One issue with equation-specific tests is that they lack specificity, in that they indicate…

Real data are unlikely to be exactly normally distributed. Ignoring non-normality will cause misleading and unreliable parameter estimates, standard error estimates, and model fit statistics. For non-normal data, researchers have proposed a distributionally-weighted least squares (DLS) estimator to combines the normal theory based generalized…

Accounting for model misspecification in Bayesian structural equation models is an active area of research. We present a uniquely Bayesian approach to misspecification that models the degree of misspecification as a parameter--a parameter akin to the correlation root mean squared residual. The misspecification parameter can be interpreted on its…

Drug repurposing refers to the process of discovering new therapeutic uses for existing medicines. Compared to traditional drug discovery, drug repurposing is attractive for its speed, cost, and reduced risk of failure. However, existing approaches for drug repurposing involve complex, computationally-intensive analytical methods that are not…

In parallel process latent growth curve mediation models, the mediation pathways from treatment to the intercept or slope of outcome through the intercept or slope of mediator are often of interest. In this study, we developed causal mediation analysis methods for these mediation pathways. Particularly, we provided causal definitions and…