Null distributions of permutation tests for two-sample, paired, and block designs are simulated using the R statistical programming language. For each design and type of data, permutation tests are compared with standard normal-theory and nonparametric tests. These examples (often using real data) provide for classroom discussion use of metrics…

The utility of the three-form design coupled with maximum likelihood methods for estimation of missing values was evaluated. Simulation studies demonstrate that maximum likelihood estimation and multiple imputation methods produce the most efficient and least biased estimates of variances and covariances for normally distributed and slightly…