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Mariur Rodriguez Moreno; Nye C. Johnson; Christopher B. Stewart; Mary L. Setelin; Adam X. Wayment; Braxton M. Felix; Scott R. Burt; David J. Michaelis – Journal of Chemical Education, 2024
We describe a three-day advanced organic laboratory experience that includes the solid-phase synthesis of an unknown three amino acid polypeptide for junior/senior undergraduate chemistry majors. Students conduct a series of 1D and 2D NMR experiments (HSQC, HMBC, TOCSY) and analyze the data to identify the side chain residues of the peptide and…
Descriptors: Scientific Concepts, Science Education, Undergraduate Students, Undergraduate Study
Venable, T. Leon – Journal of Chemical Education, 2019
In a two-step synthesis starting with Ni(CH[subscript 3]COO)[subscript 2] ยท4H[subscript 2]O and salicylaldehyde, students prepare Nethyl and N-isopropyl Ni(II) Schiff base (imine) complexes. After isolation and recrystallization, the products are characterized by room-temperature magnetic susceptibility measurements, FTIR spectroscopy, and…
Descriptors: Spectroscopy, Inorganic Chemistry, Science Laboratories, Advanced Courses
MacDonald, Gina – Journal of Chemical Education, 2008
This report describes a biochemistry laboratory that is completely project-oriented. Upper-level biology and chemistry majors work in teams to purify a protein of their choice. After the student groups have completed literature searches, ordered reagents, and made buffers they continue to learn basic protein purification and biochemical techniques…
Descriptors: Biochemistry, Student Research, Student Projects, Group Activities

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