Supportive parent-child interactions are critical for facilitating typically developing children's language and social skill development. For children who are late-to-talk, parent-child interactions may be particularly important to address as a means of supporting growth in children's early language abilities. Target Word is one parent-implemented intervention for children who are late-to-talk that teaches parents strategies for facilitating more meaningful communicative interactions with their children, but little is known about the impact of this program on parent-child interactions. The aim of the present study was to determine whether the nature of parent-child interactions changed during the virtual Target Word program and whether changes in parent-child interaction were associated with parents' participation in the virtual Target Word program. A total of 40 children between 16 and 27 months of age who were identified as late-to-talk and their caregivers were assigned to a treatment or wait-list control group. Parent-child interactions were captured virtually using Zoom at four time points and measured using the Parenting Interactions with Children: Checklist of Observations Linked to Outcomes (PICCOLO). Families completed book reading, pretend, and manipulative play tasks. While 16 of the 20 families in the treatment group completed the study, only 5 of the 20 families in the wait-list control group completed the entire study. Data were analyzed using a constrained longitudinal data analysis approach. Group differences in parent-child interactions were not statistically different at any time point. Further research is necessary to evaluate whether parent-child interactions are in fact impaired in late talkers, the psychometric properties of the PICCOLO for late talkers, and whether parent-child interactions may be assessed differently in virtual versus in-person environments.