In 2018, state leaders in Maine determined that their efforts to support children and their families were hampered by the lack of coordination among key stakeholders--early education and care providers, public school educators, and health and social services providers. Addressing these challenges would require new forms of collaboration both among state agencies and at the local level. In response, they created initiatives designed to work in tandem--a state inter-agency team and a companion initiative in 13 communities throughout the state. Maine chose to use the First 10 framework to guide and structure this work. First 10 partnerships bring together school districts, elementary schools, early childhood programs, and community agencies to improve the quality and coordination of education and care for young children and their families. They work to improve teaching and learning, deepen partnerships with families, and provide comprehensive services for children and families. The author provided technical assistance to Maine's state and local teams in support of this initiative.