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Saghazadeh, Amene; Rezaei, Nima – Journal of Autism and Developmental Disorders, 2017
Brain-derived neurotrophic factor (BDNF) plays an important role in activity-dependent synaptic plasticity. Altered blood BDNF levels have been frequently identified in people with autism spectrum disorders (ASD). There are however wide discrepancies in the evidence. Therefore, we performed the present systematic review and meta-analysis aimed at…
Descriptors: Meta Analysis, Brain Hemisphere Functions, Patients, Control Groups
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Olde Dubbelink, Linda M. E.; Geurts, Hilde M. – Journal of Autism and Developmental Disorders, 2017
Individuals with an autism spectrum disorder (ASD) are thought to encounter planning difficulties, but experimental research regarding the mastery of planning in ASD is inconsistent. By means of a meta-analysis of 50 planning studies with a combined sample size of 1755 individuals with and 1642 without ASD, we aim to determine whether planning…
Descriptors: Autism, Pervasive Developmental Disorders, Planning, Meta Analysis
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Leung, Rachel C.; Zakzanis, Konstantine K. – Journal of Autism and Developmental Disorders, 2014
Impairments in cognitive flexibility have been used to characterize the neuropsychological presentation of persons with autism spectrum disorders (ASDs). Previous studies have yielded mixed results. Our objective was to systematically review the sensitivity of cognitive flexibility measures in ASD using quantitative methods employed by…
Descriptors: Cognitive Ability, Autism, Pervasive Developmental Disorders, Neurological Impairments
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Teatero, Missy L.; Netley, Charles – Journal of Autism and Developmental Disorders, 2013
Boys are more likely than girls to be diagnosed with an autism spectrum disorder (ASD). The extreme male brain (EMB) theory of ASD suggests that fetal testosterone (FT) exposure may underlie sex differences in autistic traits. A link between the organizational effects of FT on the brain and ASD is often drawn based on research using digit ratio…
Descriptors: Brain, Literature Reviews, Meta Analysis, Males