The propensity score is the probability of treatment assignment conditional on observed baseline characteristics. The propensity score allows one to design and analyze an observational (nonrandomized) study so that it mimics some of the particular characteristics of a randomized controlled trial. In particular, the propensity score is a balancing…

In this commentary, we demonstrate how the potential outcomes framework can help understand the key identification assumptions underlying causal mediation analysis. We show that this framework can lead to the development of alternative research design and statistical analysis strategies applicable to the longitudinal data settings considered by…

A Monte Carlo study compared the statistical performance of standard and robust multilevel mediation analysis methods to test indirect effects for a cluster randomized experimental design under various departures from normality. The performance of these methods was examined for an upper-level mediation process, where the indirect effect is a fixed…

It is argued that ordinal statistical methods are often more appropriate than their more common counterparts because conclusions will be unaffected by monotonic transformation of the variables; they are more statistically robust when used appropriately; and they often correspond more closely to the researcher's goals. (SLD)

This paper illustrates an application of Efron's bootstrap to the repeated measures design. While this approach does not require parametric assumptions, it does utilize distributional information in the sample. By appropriately resampling from study data, the bootstrap may determine accurate sampling distributions for estimators, effects, or…

A particular strategy for investigating effects from a multivariate analysis of variance (MANOVA) is proposed. The strategy involves multiple two-group multivariate analyses. The analysis strategy is described in detail and illustrated with real data sets. (Author/JKS)

A new approach to time series analysis was developed. It employs a generalized transformation of the observed data to meet the assumptions of the general linear model, thus eliminating the need to identify a specific model. This approach permits alternative computational procedures, based on a generalized least squares algorithm. (Author/BW)