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Direct linkMigliavaca, Celina Borges; Stein, Cinara; Colpani, Verônica; Barker, Timothy Hugh; Ziegelmann, Patricia Klarmann; Munn, Zachary; Falavigna, Maicon – Research Synthesis Methods, 2022
Over the last decade, there has been a 10-fold increase in the number of published systematic reviews of prevalence. In meta-analyses of prevalence, the summary estimate represents an average prevalence from included studies. This estimate is truly informative only if there is no substantial heterogeneity among the different contexts being pooled.…
Descriptors: Incidence, Meta Analysis, Statistics, Statistical Distributions
Cao, Wenhao; Siegel, Lianne; Zhou, Jincheng; Zhu, Motao; Tong, Tiejun; Chen, Yong; Chu, Haitao – Research Synthesis Methods, 2021
A reference interval provides a basis for physicians to determine whether a measurement is typical of a healthy individual. It can be interpreted as a prediction interval for a new individual from the overall population. However, a reference interval based on a single study may not be representative of the broader population. Meta-analysis can…
Descriptors: Meta Analysis, Statistical Analysis, Intervals, Computation
Frömke, Cornelia; Kirstein, Mathia; Zapf, Antonia – Research Synthesis Methods, 2022
The accuracy of a diagnostic test is often expressed using a pair of measures: sensitivity (proportion of test positives among all individuals with target condition) and specificity (proportion of test negatives among all individuals without target condition). If the outcome of a diagnostic test is binary, results from different studies can easily…
Descriptors: Accuracy, Diagnostic Tests, Meta Analysis, Statistical Analysis
Riley, Richard D.; Collins, Gary S.; Hattle, Miriam; Whittle, Rebecca; Ensor, Joie – Research Synthesis Methods, 2023
Before embarking on an individual participant data meta-analysis (IPDMA) project, researchers should consider the power of their planned IPDMA conditional on the studies promising their IPD and their characteristics. Such power estimates help inform whether the IPDMA project is worth the time and funding investment, before IPD are collected. Here,…
Descriptors: Computation, Meta Analysis, Participant Characteristics, Data
Kulinskaya, Elena; Hoaglin, David C.; Bakbergenuly, Ilyas; Newman, Joseph – Research Synthesis Methods, 2021
The conventional Q statistic, using estimated inverse-variance (IV) weights, underlies a variety of problems in random-effects meta-analysis. In previous work on standardized mean difference and log-odds-ratio, we found superior performance with an estimator of the overall effect whose weights use only group-level sample sizes. The Q statistic…
Descriptors: Q Methodology, Meta Analysis, Statistical Analysis, Statistical Distributions
Wang, Chia-Chun; Lee, Wen-Chung – Research Synthesis Methods, 2019
A systematic review and meta-analysis is an important step in evidence synthesis. The current paradigm for meta-analyses requires a presentation of the means under a random-effects model; however, a mean with a confidence interval provides an incomplete summary of the underlying heterogeneity in meta-analysis. Prediction intervals show the range…
Descriptors: Meta Analysis, Computation, Statistical Analysis, Prediction
Schild, Anne H. E.; Voracek, Martin – Research Synthesis Methods, 2015
Research has shown that forest plots are a gold standard in the visualization of meta-analytic results. However, research on the general interpretation of forest plots and the role of researchers' meta-analysis experience and field of study is still unavailable. Additionally, the traditional display of effect sizes, confidence intervals, and…
Descriptors: Graphs, Visualization, Meta Analysis, Data Interpretation
