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Direct linkSaluja, Ronak; Cheng, Sierra; delos Santos, Keemo Althea; Chan, Kelvin K. W. – Research Synthesis Methods, 2019
Objective: Various statistical methods have been developed to estimate hazard ratios (HRs) from published Kaplan-Meier (KM) curves for the purpose of performing meta-analyses. The objective of this study was to determine the reliability, accuracy, and precision of four commonly used methods by Guyot, Williamson, Parmar, and Hoyle and Henley.…
Descriptors: Meta Analysis, Reliability, Accuracy, Randomized Controlled Trials
Wing, Coady; Cook, Thomas D. – Journal of Policy Analysis and Management, 2013
The sharp regression discontinuity design (RDD) has three key weaknesses compared to the randomized clinical trial (RCT). It has lower statistical power, it is more dependent on statistical modeling assumptions, and its treatment effect estimates are limited to the narrow subpopulation of cases immediately around the cutoff, which is rarely of…
Descriptors: Regression (Statistics), Research Design, Statistical Analysis, Research Problems
