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A. E. Ades; Nicky J. Welton; Sofia Dias; David M. Phillippo; Deborah M. Caldwell – Research Synthesis Methods, 2024
Network meta-analysis (NMA) is an extension of pairwise meta-analysis (PMA) which combines evidence from trials on multiple treatments in connected networks. NMA delivers internally consistent estimates of relative treatment efficacy, needed for rational decision making. Over its first 20 years NMA's use has grown exponentially, with applications…
Descriptors: Network Analysis, Meta Analysis, Medicine, Clinical Experience
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Su, Yu-Xuan; Tu, Yu-Kang – Research Synthesis Methods, 2018
Network meta-analysis compares multiple treatments in terms of their efficacy and harm by including evidence from randomized controlled trials. Most clinical trials use parallel design, where patients are randomly allocated to different treatments and receive only 1 treatment. However, some trials use within person designs such as split-body,…
Descriptors: Network Analysis, Meta Analysis, Randomized Controlled Trials, Research Design