Background: When RCTs are not feasible and time series data are available, panel data methods can be used to estimate treatment effects on outcomes, by exploiting variation in policies and conditions over time and across locations. A complication with these methods, however, is that treatment timing often varies across the sample, for example, due…

Conventional optimal design frameworks consider a narrow range of sampling cost structures that thereby constrict their capacity to identify the most powerful and efficient designs. We relax several constraints of previous optimal design frameworks by allowing for variable sampling costs in cluster-randomized trials. The proposed framework…

In paired experiments, participants are grouped into pairs with similar characteristics, and one observation from each pair is randomly assigned to treatment. The resulting treatment and control groups should be well-balanced; however, there may still be small chance imbalances. Building on work for completely randomized experiments, we propose a…

Researchers face many choices when conducting large-scale multisite individually randomized control trials. One of the most common quantities of interest in multisite RCTs is the overall average effect. Even this quantity is non-trivial to define and estimate. The researcher can target the average effect across individuals or sites. Furthermore,…

Background: Researchers are often interested in testing the effectiveness of an intervention on multiple outcomes, for multiple subgroups, at multiple points in time, or across multiple treatment groups. The resulting multiplicity of statistical hypothesis tests can lead to spurious findings of effects. Multiple testing procedures (MTPs)…

In multisite trials, learning about treatment effect variation across sites is critical for understanding where and for whom a program works. Unadjusted comparisons, however, capture "compositional" differences in the distributions of unit-level features as well as "contextual" differences in site-level features, including…

Network meta-analysis is a popular method to synthesize the information obtained in a systematic review of studies (e.g., randomized clinical trials) involving subsets of multiple treatments of interest. The dominant method of analysis employs within-study information on treatment contrasts and integrates this over a network of studies. One…

The contrary of stochastic independence splits up into two cases: pairs of events being favourable or being unfavourable. Examples show that both notions have quite unexpected properties, some of them being opposite to intuition. For example, transitivity does not hold. Stochastic dependence is also useful to explain cases of Simpson's paradox.

For binary experimental data, we discuss randomization-based inferential procedures that do not need to invoke any modeling assumptions. We also introduce methods for likelihood and Bayesian inference based solely on the physical randomization without any hypothetical super population assumptions about the potential outcomes. These estimators have…

The aim of this study was to investigate and empirically derive parameters commonly used for statistical power and sample size calculations to better inform future trial design. Towards achieving this aim, the research project leveraged the richness of the National Pupil Database (NPD) and the Education Endowment Foundation (EEF) Archive to: (1)…

Among econometricians, instrumental variable (IV) estimation is a commonly used technique to estimate the causal effect of a particular variable on a specified outcome. However, among applied researchers in the social sciences, IV estimation may not be well understood. Although there are several IV estimation primers from different fields, most…

Randomized evaluations of educational technology produce log data as a bi-product: highly granular data on student and teacher usage. These datasets could shed light on causal mechanisms, effect heterogeneity, or optimal use. However, there are methodological challenges: implementation is not randomized and is only defined for the treatment group,…

Cost-effectiveness analysis is a widely used educational evaluation tool. The randomized controlled trials that aim to evaluate the cost-effectiveness of the treatment are commonly referred to as randomized cost-effectiveness trials (RCETs). This study provides methods of power analysis for two-level multisite RCETs. Power computations take…

We present an aggregation scheme that increases power in randomized controlled trials and quasi-experiments when the intervention possesses a robust and well-articulated theory of change. Intervention studies using longitudinal data often include multiple observations on individuals, some of which may be more likely to manifest a treatment effect…

Professional development for teachers is regarded as one of the principal pathways through which we can understand and cultivate effective teaching and improve student outcomes. A critical component of studies that seek to improve teaching through professional development is the detailed assessment of the intermediate teacher development processes…