This article presents two alternative methods to null hypothesis significance testing (NHST) for improving inferences from underpowered research designs. Post hoc design analysis (PHDA) assesses whether an NHST analysis generating null findings might otherwise have had sufficient power to detect effects of plausible magnitudes. Bayesian analysis…

Null hypothesis significance testing (NHST) has been the subject of debate for decades and alternative approaches to data analysis have been proposed. This article addresses this debate from the perspective of scientific inquiry and inference. Inference is an inverse problem and application of statistical methods cannot reveal whether effects…

A reproducibility crisis afflicts a wide range of scientific and social-scientific disciplines, from epidemiology to social psychology. Improper research techniques, lack of accountability, disciplinary and political groupthink, and a scientific culture biased toward producing positive results together have produced a critical state of affairs.…

In his article, "An Alternative to Null-Hypothesis Significance Tests," Killeen (2005) urged the discipline to abandon the practice of "p[subscript obs]"-based null hypothesis testing and to quantify the signal-to-noise characteristics of experimental outcomes with replication probabilities. He described the coefficient that he…

This comment offers three descriptions of "p[subscript rep]" that start with a frequentist account of confidence intervals, draw on R. A. Fisher's fiducial argument, and do not make Bayesian assumptions. Links are described among "p[subscript rep]," "p" values, and the probability a confidence interval will capture…

D. Trafimow presented an analysis of null hypothesis significance testing (NHST) using Bayes's theorem. Among other points, he concluded that NHST is logically invalid, but that logically valid Bayesian analyses are often not possible. The latter conclusion reflects a fundamental misunderstanding of the nature of Bayesian inference. This view…

The Behrens-Fisher problem arises when one seeks to make inferences about the means of two normal populations without assuming the variances are equal. This paper presents a review of fundamental concepts and applications used to address the Behrens-Fisher problem under fiducial, Bayesian, and frequentist approaches. Methods of approximations to…