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Adolescent Substance Use in the Multimodal Treatment Study of Attention-Deficit/Hyperactivity Disorder (ADHD) (MTA) as a Function of Childhood ADHD, Random Assignment to Childhood Treatments, and Subsequent Medication
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Molina, Brooke S. G.; Hinshaw, Stephen P.; Arnold, L. Eugene; Swanson, James M.; Pelham, William E.; Hechtman, Lily; Hoza, Betsy; Epstein, Jeffery N.; Wigal, Timothy; Abikoff, Howard B.; Greenhill, Laurence L.; Jensen, Peter S.; Wells, Karen C.; Vitiello, Benedetto; Gibbons, Robert D.; Howard, Andrea; Houck, Patricia R.; Hur, Kwan; Lu, Bo; Marcus, Sue – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: To determine long-term effects on substance use and substance use disorder (SUD), up to 8 years after childhood enrollment, of the randomly assigned 14-month treatments in the multisite Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (MTA; n = 436); to test whether medication at follow-up, cumulative…
Descriptors: Prevention, Substance Abuse, Attention Deficit Hyperactivity Disorder, Adolescents
Subtypes of Aggression in Children with Attention Deficit Hyperactivity Disorder: Medication Effects and Comparison with Typical Children
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King, Sara; Waschbusch, Daniel A.; Pelham, William E.; Frankland, Bradley W.; Corkum, Penny V.; Jacques, Sophie – Journal of Clinical Child and Adolescent Psychology, 2009
We examined aggressive behavior in 6- to 12-year-old children, including 20 children with attention deficit hyperactivity disorder (ADHD) on stimulant medication, 19 children with ADHD on placebo (n = 19), and 32 controls. Children completed a laboratory provocation task designed to measure hostile, instrumental, reactive, and proactive…
Descriptors: Stimulants, Aggression, Attention Deficit Hyperactivity Disorder, Drug Therapy
Effects of Stimulant Medication on Growth Rates across 3 Years in the MTA Follow-up
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Swanson, James M.; Elliott, Glen R.; Greenhill, Laurence L.; Wigal, Timothy; Arnold, L. Eugene; Vitiello, Benedetto; Hechtman, Lily; Epstein, Jeffery N.; Pelham, William E.; Abikoff, Howard B.; Newcorn, Jeffrey H.; Molina, Brooke S. G.; Hinshaw, Stephen P.; Wells, Karen C.; Hoza, Betsy; Jensen, Peter S.; Gibbons, Robert D.; Hur, Kwan; Stehli, Annamarie; Davies, Mark; March, John S.; Conners, C. Keith; Caron, Mark; Volkow, Nora D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To evaluate the hypothesis of stimulant medication effect on physical growth in the follow-up phase of the Multimodal Treatment Study of Children With ADHD. Method: Naturalistic subgroups were established based on patterns of treatment with stimulant medication at baseline, 14-, 24-, and 36-month assessments: not medicated (n = 65),…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Norms, Statistical Analysis
Assessing Medication Effects in the MTA Study Using Neuropsychological Outcomes
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Epstein, Jeffery N.; Conners, C. Keith; Hervey, Aaron S.; Tonev, Simon T.; Arnold, L. Eugene; Abikoff, Howard B.; Elliott, Glen; Greenhill, Laurence L.; Hechtman, Lily; Hoagwood, Kimberly; Hinshaw, Stephen P.; Hoza, Betsy; Jensen, Peter S.; March, John S.; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Wells, Karen; Vitiello, Benedetto; Wigal, Timothy – Journal of Child Psychology and Psychiatry, 2006
Background: While studies have increasingly investigated deficits in reaction time (RT) and RT variability in children with attention deficit/hyperactivity disorder (ADHD), few studies have examined the effects of stimulant medication on these important neuropsychological outcome measures. Methods: 316 children who participated in the Multimodal…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Reaction Time, Drug Therapy
Behavioral and Stimulant Treatment of Hyperactive Children: A Therapy Study with Methylphenidate Probes in a Within-Subject Design.
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Pelham, William E.; And Others – Journal of Applied Behavior Analysis, 1980
Eight hyperactive children (6 to 11 years old) were treated with a behavioral intervention focusing on teacher and parent training over a period of 5 months. The results suggested that the combination of psychostimulant medication and behavior therapy may be more effective in the short term than either treatment alone. (Author)
Descriptors: Behavior Change, Behavior Modification, Children, Drug Therapy