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Stimulant Treatment over Five Years: Adherence, Effectiveness, and Adverse Effects.
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Charach, Alice; Ickowicz, Abel; Schachar, Russell – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To evaluate the impact of adherence and medication status on effectiveness and adverse effects of stimulant use in children with attention-deficit/hyperactivity disorder (ADHD) over 5 years. Method: Seventy-nine of 91 participants in a 12-month randomized controlled trial of methylphenidate and parent groups enrolled in a follow-up…
Descriptors: Psychiatry, Stimulants, Hyperactivity, Followup Studies
Treatment of ADHD with Stimulant Medications: Response to Nissen Perspective in the New England Journal of Medicine
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Biederman, Joseph; Spencer, Thomas J.; Wilens, Timothy E.; Prince, Jefferson B.; Faraone, Stephen V. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
This article is a response to Dr. Steven E. Nissen's comments (Nissen, 2006) about attention deficit/hyperactivity disorder (ADHD) and its treatment with stimulant medications. In this article, the authors refute his arguments and provide accurate information. Here, they answer the questions, such as: (1) Do stimulants increase the risk for sudden…
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Risk
A Prospective Study of Stimulant Response in Preschool Children: Insights from ROC Analyses
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Short, Elizabeth J.; Manos, Michael J.; Findling, Robert L.; Schubel, Emily A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: The purpose of this study was to examine the efficacy of psychostimulant medication in a naturalistic sample of preschoolers. Benefits and side effects for methylphenidate and mixed amphetamine salts (Adderall) were examined. Method: Twenty-eight preschoolers (ages 4.0-5.9) participated in the present investigation. They were obtained…
Descriptors: Psychiatry, Pharmacology, Stimulants, Preschool Children
Does Prolonged Therapy with a Long-Acting Stimulant Suppress Growth in Children with ADHD?
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Spencer, Thomas J.; Faraone, Stephen V.; Biederman, Joseph; Lerner, Marc; Cooper, Kimberly M.; Zimmerman, Brenda – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To investigate whether prolonged therapy with a long-acting stimulant affects growth in children with attention-deficit/hyperactivity disorder (ADHD). Method: One hundred seventy-eight children ages 6 to 13 years received OROS methylphenidate (OROS MPH, CONCERTA) for at least 21 months. Height and weight were measured monthly during the…
Descriptors: Body Height, Body Weight, Drug Therapy, Stimulants
Sequential Pharmacotherapy for Children with Comorbid Attention-Deficit/hyperactivity and Anxiety Disorders.
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Abikoff, Howard; McGough, James; Vitiello, Benedetto; McCracken, James; Davies, Mark; Walkup, John; Riddle, Mark; Oatis, Melvin; Greenhill, Laurence; Skrobala, Anne; March, John; Gammon, Pat; Robinson, James; Lazell, Robert; McMahon, Donald J.; Ritz, Louise – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: Attention-deficit/hyperactivity disorder (ADHD) is often accompanied by clinically significant anxiety, but few empirical data guide treatment of children meeting full DSM-IV criteria for ADHD and anxiety disorders (ADHD/ANX). This study examined the efficacy of sequential pharmacotherapy for ADHD/ANX children. Method: Children, age 6…
Descriptors: Psychiatry, Teacher Evaluation, Stimulants, Rating Scales
Stimulant Treatment over 5 Years: Effects on Growth
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Charach, Alice; Figueroa, Max; Chen, Shirley; Ickowicz, Abel; Schachar, Russell – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: Long-term effects of psychostimulants on growth in height and in weight are investigated in children with attention-deficit/hyperactivity disorder. Method: Participants were 79 children, 6 to 12 years of age, with attention-deficit/hyperactivity disorder, who were followed annually for up to 5 years, between the years 1993 and 1994 and…
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Body Height
Comparative Effects of Methylphenidate and Mixed Salts Amphetamine on Height and Weight in Children with Attention-Deficit/Hyperactivity Disorder
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Pliszka, Steven R.; Matthews, Thomas L.; Braslow, Kenneth J.; Watson, Melissa A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To determine whether methylphenidate (MPH) and mixed salts amphetamine (MSA) have different effects on growth in children with attention-deficit/hyperactivity disorder. Method: Patients treated for at least 1 year with MPH or MSA were identified. A linear regression was performed to determine the effect of stimulant type, patient…
Descriptors: Attention Deficit Disorders, Children, Stimulants, Hyperactivity
ADHD Treatment with Once-Daily OROS Methylphenidate: Final Results from a Long-term Open-Label Study
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Wilens, Timothy; McBurnett, Keith; Stein, Mark; Lerner, Marc; Spencer, Thomas; Wolraich, Mark – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: Few studies have assessed effectiveness and tolerability of stimulants when used for prolonged periods in children with attention-deficit/hyperactivity disorder (ADHD). This article presents final results from an open-label, multisite study of a once-daily formulation of methylphenidate (MPH), OROS[R] MPH. Method: Subjects received OROS…
Descriptors: Hyperactivity, Attention Deficit Disorders, Outcomes of Treatment, Children
Characteristics of Adolescents and Young Adults with ADHD Who Divert or Misuse Their Prescribed Medications
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Wilens, Timothy E.; Gignac, Martin; Swezey, Allison; Monuteaux, Michael C.; Biederman, Joseph – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: Little is known about the risks and characteristics of attention-deficit/hyperactivity disorder (ADHD) patients who misuse or divert their stimulant medications. As part of a 10-year longitudinal study of youths with ADHD, the authors evaluated medication diversion or misuse at the last follow-up period. Method: Structured psychiatric…
Descriptors: Patients, Adolescents, Young Adults, Siblings
Children with ADHD Treated with Long-Term Methylphenidate and Multimodal Psychosocial Treatment: Impact on Parental Practices
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Hechtman, Lily; Abikoff, Howard; Klein, Rachel G.; Greenfield, Brian; Etcovitch, Joy; Cousins, Lorne; Fleiss, Karen; Weiss, Margaret; Pollack, Simcha – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To test the hypothesis that multimodal psychosocial intervention, which includes parent training, combined with methylphenidate significantly enhances the behavior of parents of children with attention-deficit/hyperactivity disorder (ADHD), compared with methylphenidate alone and compared with methylphenidate and nonspecific…
Descriptors: Attention Control, Psychiatry, Psychotherapy, Parents
Pharmacological Management of Treatment-Induced Insomnia in ADHD
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Kratochvil, Christopher J.; Lake, Marybeth; Pliszka, Steven R.; Walkup, John T. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
A 7-year-old girl with attention-deficit/hyperactivity disorder (ADHD), combined subtype, and oppositional defiant disorder presents with a complaint of marked insomnia. Her parents describe 60 to 90 minutes of nightly initial insomnia that began with the initiation of 36 mg OROS methylphenidate (Concerta) 2 months ago. Behavioral interventions…
Descriptors: Drug Therapy, Stimulants, Sleep, Hyperactivity
Sleep Hygiene and Melatonin Treatment for Children and Adolescents with ADHD and Initial Insomnia
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Weiss, Margaret D.; Wasdell, Michael B.; Bomben, Melissa M.; Rea, Kathleen J.; Freeman, Roger D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To evaluate the efficacy of sleep hygiene and melatonin treatment for initial insomnia in children with attention-deficit/hyperactivity disorder (ADHD). Method: Twenty-seven stimulant-treated children (6-14 years of age) with ADHD and initial insomnia (greater than 60 minutes) received sleep hygiene intervention. Nonresponders were…
Descriptors: Intervention, Hygiene, Stimulants, Hyperactivity
Stimulant-Related Reductions of Growth Rates in the PATS
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Swanson, James; Greenhill, Laurence; Wigal, Tim; Kollins, Scott; Stehli, Annamarie; Davies, Mark; Chuang, Shirley; Vitiello, Benedetto; Skrobala, Anne; Posner, Kelly; Abikoff, Howard; Oatis, Melvin; McCracken, James; McGough, James; Riddle, Mark; Ghuman, Jaswinder; Cunningham, Charles; Wigal, Sharon – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To investigate growth of children with attention-deficit/hyperactivity disorder (ADHD) in the Preschool ADHD Treatment Study (PATS) before and after initiation of treatment with methylphenidate at titrated doses (average, 14.2 mg/day) administered three times daily, 7 days/week for approximately equal to 1 year. Method: The heights and…
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Body Height
Stimulant Medication Effects in a Summer Treatment Program among Young Children with Attention-Deficit/Hyperactivity Disorder
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Chacko, Anil; Pelham, William E., Jr.; Gnagy, Elizabeth M.; Greiner, Andrew; Vallano, Gary; Bukstein, Oscar; Rancurello, Michael – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: This study examined the effectiveness of stimulant medication on multiple domains of functioning in 36 young (5 to 6 years old) children diagnosed with attention-deficit/hyperactivity disorder (ADHD). Method: Five- and 6-year-old children attending a summer treatment program between 1987 and 1997 underwent a randomized clinical…
Descriptors: Social Behavior, Young Children, Stimulants, Hyperactivity
Treatment Effects of Methylphenidate on Cognitive Functioning in Children with Mental Retardation and ADHD
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Pearson, Deborah A.; Santos, Cynthia W.; Casat, Charles D.; Lane, David M.; Jerger, Susan W.; Roache, John D.; Loveland, Katherine A.; Lachar, David; Faria, Laura P.; Payne, Christa D.; Cleveland, Lynne A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: Cognitive effects of stimulant medication were investigated in children with mental retardation (MR) and attention-deficit/hyperactivity disorder (ADHD). Method: Performance on tasks tapping sustained attention, visual and auditory selective attention, inhibition, and immediate memory was assessed for 24 children (mean age 10.9 years)…
Descriptors: Stimulants, Mental Retardation, Inhibition, Hyperactivity
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