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Direct linkIliyan Ivanov; Beth Krone; Kurt Schulz; Riaz B. Shaik; Muhammad A. Parvaz; Jeffrey H. Newcorn – Journal of Attention Disorders, 2024
Background: Research examining the potential effects of stimulant exposure in childhood on subsequent development of substance use disorder (SUD) have focused on differences in the brain reward system as a function of risk. Methods: 18 drug naïve children ages 7 to 12 years (11 High Risk [ADHD + ODD/CD]; 7 Low Risk [ADHD only]), underwent fMRI…
Descriptors: Children, Attention Deficit Hyperactivity Disorder, Comorbidity, Drug Therapy
Benjamin Johnson; Daniel Stjepanovic; Janni Leung; Gary C. K. Chan – Journal of Attention Disorders, 2025
Background: The shortage of prescription stimulants is an ongoing issue that is impacting the ability of individuals with ADHD to access their medication. Amidst concerns that this shortage may have a substantial impact on individuals' ability to manage their symptoms effectively, this research seeks to understand the experiences and consequences…
Descriptors: Attention Deficit Hyperactivity Disorder, Drug Therapy, Stimulants, Access to Health Care
Ng, Rowena; Heinrich, Kimberley; Hodges, Elise – Journal of Mental Health Research in Intellectual Disabilities, 2020
Introduction: The primary aim of this retrospective study was to assess differential associations between sleep disturbances with externalizing/internalizing problems, ADHD profiles (inattention, hyperactivity/impulsivity), and social impairment among children with ADHD, autism spectrum disorder (ASD), and comorbid diagnoses (ASD+ADHD). Methods:…
Descriptors: Sleep, Correlation, Comorbidity, Attention Deficit Hyperactivity Disorder
Arnold, L. Eugene – Journal of Child Psychology and Psychiatry, 2013
This randomized clinical trial of methylphenidate in children with intellectual disability (ID) by Simonoff et al. (2013) advances the field in several ways useful to clinicians. The large ("N" = 122) widely representative sample more definitively confirms findings previously reported from smaller studies and studies with a differently…
Descriptors: Attention Deficit Hyperactivity Disorder, Symptoms (Individual Disorders), Mental Retardation, Developmental Disabilities
Molina, Brooke S. G.; Hinshaw, Stephen P.; Arnold, L. Eugene; Swanson, James M.; Pelham, William E.; Hechtman, Lily; Hoza, Betsy; Epstein, Jeffery N.; Wigal, Timothy; Abikoff, Howard B.; Greenhill, Laurence L.; Jensen, Peter S.; Wells, Karen C.; Vitiello, Benedetto; Gibbons, Robert D.; Howard, Andrea; Houck, Patricia R.; Hur, Kwan; Lu, Bo; Marcus, Sue – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: To determine long-term effects on substance use and substance use disorder (SUD), up to 8 years after childhood enrollment, of the randomly assigned 14-month treatments in the multisite Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (MTA; n = 436); to test whether medication at follow-up, cumulative…
Descriptors: Prevention, Substance Abuse, Attention Deficit Hyperactivity Disorder, Adolescents
Tannock, Rosemary; Frijters, Jan C.; Martinussen, Rhonda; White, Erin Jacquelyn; Ickowicz, Abel; Benson, Nancy J.; Lovett, Maureen W. – Journal of Learning Disabilities, 2018
To evaluate the relative efficacy of two reading programs with and without adjunctive stimulant medication for children with attention-deficit/hyperactivity disorder and comorbid reading disorder (ADHD+RD). Sixty-five children (7-11 years in age) were assigned randomly to one of three intensive remedial academic programs (phonologically or…
Descriptors: Intervention, Attention Deficit Hyperactivity Disorder, Comorbidity, Child Behavior
Brossard-Racine, Marie; Shevell, Michael; Snider, Laurie; Belanger, Stacey Ageranioti; Majnemer, Annette – Research in Developmental Disabilities: A Multidisciplinary Journal, 2012
Motor difficulties are common in children with Attention Deficit Hyperactivity Disorder (ADHD). Although preliminary evidence has suggested that methylphenidate can improve the motor skills in children with ADHD and Developmental Coordination Disorder (DCD), the effect of stimulant medication on motor performance in children newly diagnosed with…
Descriptors: Psychomotor Skills, Children, Attention Deficit Hyperactivity Disorder, Stimulants
Reichow, Brian; Volkmar, Fred R.; Bloch, Michael H. – Journal of Autism and Developmental Disorders, 2013
Many children with pervasive developmental disorders (PDD) exhibit behaviors and symptoms of attention-deficit/hyperactivity disorder (ADHD). We sought to determine the relative efficacy of medications for treating ADHD symptoms in children with PDD by identifying all double-blind, randomized, placebo-controlled trials examining the efficacy of…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Outcomes of Treatment
Brackenridge, Rachel; McKenzie, Karen; Murray, George C.; Quigley, April – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
This study investigated whether methylphenidate is effective in improving response inhibition in children with Attention Deficit Hyperactivity Disorder (ADHD). Children with ADHD were compared with normally developing children on measures of response inhibition. Participants with ADHD were compared across two conditions--medicated and unmedicated.…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Drug Therapy, Inhibition
Mahon, Anthony D.; Woodruff, Megan E.; Horn, Mary P.; Marjerrison, Andrea D.; Cole, Andrew S. – Adapted Physical Activity Quarterly, 2012
The effect of stimulant medication use by children with attention deficit/hyperactivity disorder (ADHD) on the rating of perceived exertion (RPE)--heart rate (HR) relationship was examined. Children with ADHD (n = 20; 11.3 [plus or minus] 1.8 yrs) and children without ADHD (n = 25; 11.2 [plus or minus] 2.1 yrs) were studied. Children with ADHD…
Descriptors: Attention Deficit Hyperactivity Disorder, Control Groups, Metabolism, Stimulants
Faraone, Stephen V. – Journal of Attention Disorders, 2012
Objective: An earlier meta-analysis of pediatric clinical trials indicated that lisdexamfetamine dimesylate (LDX) had a greater effect size than other stimulant medications. This work tested the hypothesis that the apparent increased efficacy was artifactual. Method: The authors assessed two potential artifacts: an unusually high precision of…
Descriptors: Stimulants, Intervals, Effect Size, Drug Therapy
Wilens, Timothy E.; Bukstein, Oscar; Brams, Matthew; Cutler, Andrew J.; Childress, Ann; Rugino, Thomas; Lyne, Andrew; Grannis, Kara; Youcha, Sharon – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: To examine efficacy, tolerability, and safety of guanfacine extended release (GXR; less than or equal to 4 mg/d) adjunctive to a long-acting psychostimulant for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents 6 to 17 years of age with suboptimal, but partial, response to psychostimulant…
Descriptors: Attention Deficit Hyperactivity Disorder, Safety, Rating Scales, Severity (of Disability)
Olfson, Mark; Huang, Cecilia; Gerhard, Tobias; Winterstein, Almut G.; Crystal, Stephen; Allison, Paul D.; Marcus, Steven C. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: This study examined associations between stimulant use and risk of cardiovascular events and symptoms in youth with attention-deficit/hyperactivity disorder and compared the risks associated with methylphenidate and amphetamines. Method: Claims were reviewed of privately insured young people 6 to 21 years old without known…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Cohort Analysis, Risk
Brossard-Racine, Marie; Majnemer, Annette; Shevell, Michael; Snider, Laurie; Belanger, Stacey Ageranioti – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
Preliminary evidence suggests that children with Attention Deficit Hyperactivity Disorder (ADHD) may exhibit handwriting difficulties. However, the exact nature of these difficulties and the extent to which they may relate to motor or behavioural difficulties remains unclear. The aim of this study was to describe handwriting capacity in children…
Descriptors: Evidence, Attention Deficit Hyperactivity Disorder, Handwriting, Motor Development
Hammerness, Paul G.; Perrin, James M.; Shelley-Abrahamson, Rachel; Wilens, Timothy E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: This review provides an update on the cardiovascular impact of therapeutic stimulant-class medication for children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Method: Relevant clinical literature was ascertained using PubMed searches limited to human studies and the English language as of May 2011. Current…
Descriptors: Attention Deficit Hyperactivity Disorder, Metabolism, Stimulants, Adolescents
