Hippocampal-dependent tasks often involve specific associations among stimuli (including egocentric information), and such tasks are therefore prone to interference from irrelevant task strategies before a correct strategy is found. Using an object-place paired-associate task, we investigated changes in neural firing patterns in the hippocampus in…

One symptom of depression is loss of motivation, which can be defined as responsiveness to response-eliciting stimuli and quantified as reward-related behavioral output. Long-term changes in reward-related behavior have been shown to follow early life stress. Most rodent studies investigating the effects of postnatal separation, an early stress,…

Three-month-old infants learned to activate a crib mobile by means of operant footkicks. Retention of the conditioned response was assessed in the presence of the nonmoving mobile. Although forgetting is typically complete after an 8-day retention interval, infants who received a reactivation treatment, a brief exposure to the reinforcer 24 hours…