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Direct linkPuglisi, Jose L.; Negroni, Jorge A.; Chen-Izu, Ye; Bers, Donald M. – Advances in Physiology Education, 2013
The force-frequency relationship has intrigued researchers since its discovery by Bowditch in 1871. Many attempts have been made to construct mathematical descriptions of this phenomenon, beginning with the simple formulation of Koch-Wesser and Blinks in 1963 to the most sophisticated ones of today. This property of cardiac muscle is amplified by…
Descriptors: Feedback (Response), Mathematical Models, Prediction, Intervals
