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Direct linkGeorgiades, Stelios; Tait, Peter A.; McNicholas, Paul D.; Duku, Eric; Zwaigenbaum, Lonnie; Smith, Isabel M.; Bennett, Teresa; Elsabbagh, Mayada; Kerns, Connor M.; Mirenda, Pat; Ungar, Wendy J.; Vaillancourt, Tracy; Volden, Joanne; Waddell, Charlotte; Zaidman-Zait, Anat; Gentles, Stephen; Szatmari, Peter – Journal of Autism and Developmental Disorders, 2022
This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a "turning…
Descriptors: Symptoms (Individual Disorders), Severity (of Disability), Children, Autism
McVey, Alana J.; Liu, Quinn; Bedford, Saashi A.; Zaidman-Zait, Anat; Szatmari, Peter; Smith, Isabel M.; Vaillancourt, Tracy; Zwaigenbaum, Lonnie; Bennett, Teresa; Duku, Eric; Elsabbagh, Mayada; Georgiades, Stelios; Kerns, Connor M. – Autism: The International Journal of Research and Practice, 2023
Research regarding autistic children's sibling relationship quality is mixed, although some literature suggests poorer quality compared to children with other disabilities or who are neurotypical. Little is known about how the clinical characteristics of autistic children relate to parent perceptions of sibling relationship quality. We drew data…
Descriptors: Autism Spectrum Disorders, Parent Attitudes, Sibling Relationship, Children
Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Journal of Autism and Developmental Disorders, 2021
Despite considerable progress in characterizing the early signs of autism spectrum disorder (ASD), more remains to be learned about how symptoms emerge in the first year of life. Parents with a new baby who already had at least one biological child diagnosed with ASD (high-risk) or no family history of ASD (low-risk) completed two measures when…
Descriptors: Siblings, Screening Tests, Autism, Pervasive Developmental Disorders
Carter Leno, Virginia; Wright, Nicola; Pickles, Andrew; Bedford, Rachael; Zaidman-Zait, Anat; Kerns, Connor; Mirenda, Pat; Zwaigenbaum, Lonnie; Duku, Eric; Bennett, Teresa; Georgiades, Stelios; Smith, Isabel; Vaillancourt, Tracy; Szatmari, Peter; Elsabbagh, Mayada – Autism: The International Journal of Research and Practice, 2022
Mental health problems are prevalent in autistic youth, but the underpinning mechanisms are not well explored. In neurotypical youth, stressful life events are an established risk factor for mental health problems. This study tested longitudinal bidirectional associations between family-level stressful life events and mental health problems and…
Descriptors: Autism Spectrum Disorders, Family Environment, Stress Variables, Children
Zwaigenbaum, Lonnie; Bryson, Susan E.; Brian, Jessica; Smith, Isabel M.; Sacrey, Lori; Armstrong, Vickie; Roberts, Wendy; Szatmari, Peter; Garon, Nancy; Vaillancourt, Tracy; Roncadin, Caroline – Child Development, 2021
The objectives were to characterize behavioral signs of autism spectrum disorder (ASD) in younger siblings of diagnosed children (high-risk; HR) and examine classification features of the Autism Observation Scale for Infants (AOSI). Participants (501 HR and 180 low-risk [LR]) were assessed between 6 and 18 months using the AOSI and at age 3 for…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Infant Behavior
Brian, Jessica; Drmic, Irene; Roncadin, Caroline; Dowds, Erin; Shaver, Chantelle; Smith, Isabel M.; Zwaigenbaum, Lonnie; Sacrey, Lori-Ann R.; Bryson, Susan E. – Autism: The International Journal of Research and Practice, 2022
Recent efforts have focused on developing and evaluating early intervention for toddlers with probable or emerging autism spectrum disorder. Parent-mediated approaches have gained traction, with mounting evidence of efficacy, but a research-to-practice gap exists, and community effectiveness remains to be firmly established. We report outcomes of…
Descriptors: Autism Spectrum Disorders, Early Intervention, Toddlers, Parents
Lee, Vivian; Duku, Eric; Zwaigenbaum, Lonnie; Bennett, Teresa; Szatmari, Peter; Elsabbagh, Mayada; Kerns, Connor; Mirenda, Pat; Smith, Isabel M.; Ungar, Wendy J.; Vaillancourt, Tracy; Volden, Joanne; Waddell, Charlotte; Zaidman-Zait, Anat; Thompson, Ann; Georgiades, Stelios – Autism: The International Journal of Research and Practice, 2020
Temperament is a construct that is relatively stable over time but varies between individuals. Research suggests that children with autism spectrum disorder have a 'reactive' temperament profile when compared to peers with or without disabilities. However, our understanding of how temperament varies within children with autism and how it relates…
Descriptors: Personality Traits, Severity (of Disability), Symptoms (Individual Disorders), Behavior Problems
Talbott, Meagan R.; Dufek, Sarah; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Rogers, Sally J. – Journal of Autism and Developmental Disorders, 2020
Families with early concerns about infant symptoms of ASD have limited access to experienced professionals for screening and guidance. Telehealth has been used to reduce access disparities in other pediatric populations and has shown promise in parent-implemented interventions for ASD. We investigated the feasibility of a novel level-2 telehealth…
Descriptors: Autism, Pervasive Developmental Disorders, Infants, Parents
Lee, Helen Y.; Vigen, Cheryl; Zwaigenbaum, Lonnie; Smith, Isabel M.; Brian, Jessica; Watson, Linda R.; Crais, Elizabeth R.; Baranek, Grace T. – Autism: The International Journal of Research and Practice, 2021
This study examines the construct validity of the First-Year Inventory 2.0 with respect to other established instruments in a sample of high-risk infant siblings of children with Autism Spectrum Disorder. The First-Year Inventory 2.0 is a parent-report screening instrument designed to identify 12-month-old infants at risk for an eventual diagnosis…
Descriptors: Test Validity, Construct Validity, Autism, Pervasive Developmental Disorders
Raza, Sarah; Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Journal of Autism and Developmental Disorders, 2020
Social-emotional behavior in autism spectrum disorder (ASD) was examined among high-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers. Caregivers completed the Infant-Toddler Social Emotional Assessment (ITSEA) at 18 months, and blind diagnostic assessment for ASD was conducted at 36 months.…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Clinical Diagnosis
Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Szatmari, Peter; Bryson, Susan; Georgiades, Stelios; Brian, Jessica; Smith, Isabel M.; Vaillancourt, Tracy; Garon, Nancy; Roncadin, Caroline; Elsabbagh, Mayada – Journal of Autism and Developmental Disorders, 2017
Prospective studies of infant siblings of children diagnosed with autism spectrum disorder (ASD) provide a unique opportunity to characterize ASD as it unfolds. A critical question that remains unanswered is whether and how these children with ASD resemble other children identified from the community, including those with no family history. The…
Descriptors: Autism, Pervasive Developmental Disorders, Preschool Children, Symptoms (Individual Disorders)
Brian, Jessica; Bryson, Susan E.; Smith, Isabel M.; Roberts, Wendy; Roncadin, Caroline; Szatmari, Peter; Zwaigenbaum, Lonnie – Autism: The International Journal of Research and Practice, 2016
Considerable evidence on autism spectrum disorder emergence comes from longitudinal high-risk samples (i.e. younger siblings of children with autism spectrum disorder). Diagnostic stability to age 3 is very good when diagnosed as early as 18-24 months, but sensitivity is weaker, and relatively little is known beyond toddlerhood. We examined…
Descriptors: Autism, Pervasive Developmental Disorders, Clinical Diagnosis, Toddlers
Georgiades, Stelios; Boyle, Michael; Szatmari, Peter; Hanna, Steven; Duku, Eric; Zwaigenbaum, Lonnie; Bryson, Susan; Fombonne, Eric; Volden, Joanne; Mirenda, Pat; Smith, Isabel; Roberts, Wendy; Vaillancourt, Tracy; Waddell, Charlotte; Bennett, Teresa; Elsabbagh, Mayada; Thompson, Ann – Journal of Autism and Developmental Disorders, 2014
The latent class structure of autism symptoms from the time of diagnosis to age 6 years was examined in a sample of 280 children with autism spectrum disorder. Factor mixture modeling was performed on 26 algorithm items from the Autism Diagnostic Interview-Revised at diagnosis (Time 1) and again at age 6 (Time 2). At Time 1, a…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Children
Georgiades, Stelios; Szatmari, Peter; Boyle, Michael; Hanna, Steven; Duku, Eric; Zwaigenbaum, Lonnie; Bryson, Susan; Fombonne, Eric; Volden, Joanne; Mirenda, Pat; Smith, Isabel; Roberts, Wendy; Vaillancourt, Tracy; Waddell, Charlotte; Bennett, Teresa; Thompson, Ann – Journal of Child Psychology and Psychiatry, 2013
Background: Autism spectrum disorder (ASD) is characterized by notable phenotypic heterogeneity, which is often viewed as an obstacle to the study of its etiology, diagnosis, treatment, and prognosis. On the basis of empirical evidence, instead of three binary categories, the upcoming edition of the DSM 5 will use two dimensions--social…
Descriptors: Pervasive Developmental Disorders, Autism, Student Characteristics, Social Development
Bennett, Teresa; Boyle, Michael; Georgiades, Katholiki; Georgiades, Stelios; Thompson, Ann; Duku, Eric; Bryson, Susan; Fombonne, Eric; Vaillancourt, Tracy; Zwaigenbaum, Lonnie; Smith, Isabel; Mirenda, Pat; Roberts, Wendy; Volden, Joanne; Waddell, Charlotte; Szatmari, Peter – Journal of Child Psychology and Psychiatry, 2012
Background: Maximizing measurement accuracy is an important aim in child development assessment and research. Parents are essential informants in the diagnostic process, and past research suggests that certain parental characteristics may influence how they report information about their children. This has not been studied in autism spectrum…
Descriptors: Structural Equation Models, Autism, Depression (Psychology), Child Development
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