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Sasson, Noah J.; Bottema-Beutel, Kristen – Autism: The International Journal of Research and Practice, 2022
Studies of autistic traits in the general population are becoming increasingly prevalent. In this letter to the editor, we caution researchers against framing and interpreting studies of autistic traits in the general population as extending to autism and implore them to be clear about when their study sample does and does not include autistic…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Research
Godoy-Giménez, M.; González-Rodríguez, A.; Cañadas, F.; Estévez, A. F.; Sayans-Jiménez, P. – Journal of Autism and Developmental Disorders, 2022
Although, the operationalization of the autism spectrum disorder has been updated around two domains, the broad autism phenotype (BAP) one has not. Additionally, the items of the three common BAP measures, the Broad Autism Phenotype Questionnaire (BAPQ), the Autism Quotient, and the Social Responsiveness Scale (SRS), remain organized around a…
Descriptors: Autism, Pervasive Developmental Disorders, Measurement, Screening Tests
Zhu, Jiang; Hua, Xueying; Yang, Ting; Guo, Min; Li, Qiu; Xiao, Lu; Li, Ling; Chen, Jie; Li, Tingyu – Journal of Autism and Developmental Disorders, 2022
Metabolic disturbance may be implicated in the pathogenesis of autism. This study aimed to investigate the gut metabolomic profiles of autistic children and to analyze potential interaction between gut metabolites with autistic symptoms and neurodevelopment levels. We involved 120 autistic and 60 neurotypical children. Autistic symptoms and…
Descriptors: Metabolism, Autism, Pervasive Developmental Disorders, Children
Karagözlü, Selen; Dalgiç, Buket; Iseri, Elvan – Journal of Autism and Developmental Disorders, 2022
To evaluate the relationship between the severity of autism, severity of gastrointestinal symptoms and serum zonulin levels as a marker of increased intestinal permeability in children. Serum zonulin levels were determined in 56 children with ASDs and 55 healthy children. The severity of gastrointestinal symptoms and ASD symptoms was assessed with…
Descriptors: Severity (of Disability), Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders)
Tubío-Fungueiriño, María; Cruz, Sara; Sampaio, Adriana; Carracedo, Angel; Fernández-Prieto, Montse – Journal of Autism and Developmental Disorders, 2021
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with increasing prevalence, and a male-to-female ratio of 4:1. Research has been suggesting that discrepancy in prevalence may be due to the fact that females camouflage their symptoms. In this study, we aimed to systematically review evidence on the camouflage effect in females with…
Descriptors: Social Adjustment, Females, Autism, Pervasive Developmental Disorders
Lai, Meng-Chuan – Autism: The International Journal of Research and Practice, 2022
The clinical diagnostic process for autism is complex, especially because of the high co-occurrence with other neurodevelopmental and mental health conditions (Gillberg, 2010; Lai et al., 2019). Diagnosis is more complicated in youth and adults than in younger children because life experience and development affect presentation. In particular, it…
Descriptors: Autism, Pervasive Developmental Disorders, Clinical Diagnosis, Comorbidity
Li, Jinglun; Chen, Xiu; Zheng, Ruwen; Chen, Ai; Zhou, Yan; Ruan, Jianghai – Journal of Autism and Developmental Disorders, 2022
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. The associations between the cerebellum and clinical traits remain unclear. We performed amplitude of low-frequency fluctuation (ALFF) analysis to explore the associations between spontaneous brain activity and clinical traits. 361 juvenile ASD patients were included from the ABIDEII…
Descriptors: Autism, Pervasive Developmental Disorders, Brain, Symptoms (Individual Disorders)
Law, Mei L.; Singh, Jatinder; Mastroianni, Mathilde; Santosh, Paramala – Journal of Autism and Developmental Disorders, 2022
Prodromal symptoms of Autism Spectrum Disorder (ASD) have been detected within the first year of life. This review evaluated evidence from randomized controlled trials (RCTs) of parent-mediated interventions for infants under 24 months who are at risk for ASD. Electronic databases, including grey literature, were searched up till November 2019.…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Intervention
Lee, Inn-Chi; Wang, Yu-Hsun; Chiou, Jeng-Yuan; Wei, James Cheng-Chung – Journal of Autism and Developmental Disorders, 2022
We analyzed claims data from the Taiwan National Health Insurance database, which contains data of 23.5 million Taiwan residents. We included children born after January 1, 2000 who had received a diagnosis of autism spectrum disorders (ASD). Patients who were not diagnosed with ASD were included in the control group. The ASD prevalence was 517 in…
Descriptors: Foreign Countries, Perinatal Influences, Autism, Pervasive Developmental Disorders
Horinouchi, Tomoko; Maeyama, Kaori; Nagai, Masashi; Mizobuchi, Masami; Takagi, Yasuko; Okada, Yuka; Kato, Takeshi; Nishimura, Mio; Kawasaki, Yoko; Yoshioka, Mieko; Takada, Satoshi; Matsumoto, Hisayuki; Nakamachi, Yuji; Saegusa, Jun; Fukushima, Sachiyo; Fujioka, Kazumichi; Tomioka, Kazumi; Nagase, Hiroaki; Nozu, Kandai; Iijima, Kazumoto; Nishimura, Noriyuki – Journal of Autism and Developmental Disorders, 2022
Neonatal jaundice has been suggested as a perinatal risk factor for autism spectrum disorder (ASD). We examined UGT1A1 polymorphisms to assess the potential of neonatal jaundice as a risk factor for ASD in children by using DNA extracted from preserved umbilical cord. In total, 79 children with ASD were genotyped for "UGT1A1*28"…
Descriptors: Neonates, Physiology, Biochemistry, Children
Wood-Downie, Henry; Wong, Bonnie; Kovshoff, Hanna; Mandy, William; Hull, Laura; Hadwin, Julie A. – Journal of Autism and Developmental Disorders, 2021
This study investigated sex/gender differences in camouflaging with children and adolescents (N = 84) with and without an autism diagnosis/increased levels of autistic traits using two conceptualisations/operationalisations of camouflaging. A significant group-by-gender interaction using ANCOVA, with the covariate of verbal IQ, reflected similar…
Descriptors: Gender Differences, Symptoms (Individual Disorders), Children, Adolescents
Tanner, Amy; Dounavi, Katerina – Journal of Autism and Developmental Disorders, 2021
Pre-diagnostic intervention for autism spectrum disorder (ASD) allows symptoms to be addressed as they emerge, often between six to 18 months, rather than after the full onset of the disorder. A systematic literature review, spanning the previous six years was conducted in order to provide an updated review looking at the earliest behavior…
Descriptors: Infants, Autism, Pervasive Developmental Disorders, Early Intervention
Radoeva, Petya D.; Ballinger, Kristen; Ho, Theodore; Webb, Sara J.; Stobbe, Gary A. – Journal of Autism and Developmental Disorders, 2022
Autistic individuals are at risk for developing depression though the risk and protective factors for co-occurring depression in autistic individuals are not yet fully characterized. In this retrospective medical chart review study, we explored factors associated with self-reported depressive symptoms (Patient Health Questionnaire-9) in autistic…
Descriptors: At Risk Persons, Depression (Psychology), Autism, Pervasive Developmental Disorders
Atherton, Gray; Edisbury, Emma; Piovesan, Andrea; Cross, Liam – Journal of Autism and Developmental Disorders, 2022
A significant proportion of autistic adults today were not diagnosed until later in life, a group referred to as the 'lost generation,' which may affect mental health. In Study 1 we explored quality of life and autistic trait levels in 420 autistic and TD adults, and in Study 2 we explored the experiences of 8 autistic adults diagnosed as adults.…
Descriptors: Autism, Pervasive Developmental Disorders, Clinical Diagnosis, Age
Marriott, Elise; Stacey, James; Hewitt, Olivia Mary; Verkuijl, Nienke E. – Journal of Autism and Developmental Disorders, 2022
Despite autism being highly heritable, this study is the first to investigate the experiences of parents of autistic children who have significant autistic traits themselves. Eight parents of autistic children with significant autistic traits themselves were interviewed regarding their parenting experiences. In line with what has previously been…
Descriptors: Parents, Autism, Pervasive Developmental Disorders, Parent Child Relationship