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Cavanagh, James F.; Grundler, Theo O. J.; Frank, Michael J.; Allen, John J. B. – Neuropsychologia, 2010
Larger error-related negativities (ERNs) have been consistently found in obsessive-compulsive disorder (OCD) patients, and are thought to reflect the activities of a hyperactive cortico-striatal circuit during action monitoring. We previously observed that obsessive-compulsive (OC) symptomatic students (non-patients) have larger ERNs during errors…
Descriptors: Competition, Patients, Memory, Anatomy
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Ursu, Stefan; Carter, Cameron S. – Neuropsychologia, 2009
Orbitofrontal cortical (OFC) dysfunction has been repeatedly involved in obsessive-compulsive disorder, but the precise significance of this abnormality is still unclear. Current neurocognitive models propose that specific areas of the OFC contribute to behavioral regulation by representing the anticipated affective value of future events. This…
Descriptors: Cues, Conflict, Hyperactivity, Patients