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Visual Disengagement: Genetic Architecture and Relation to Autistic Traits in the General Population
Peer reviewed
Direct linkSiqueiros Sanchez, Monica; Pettersson, Erik; Kennedy, Daniel P.; Bölte, Sven; Lichtenstein, Paul; D'Onofrio, Brian M.; Falck-Ytter, Terje – Journal of Autism and Developmental Disorders, 2020
Visual disengagement has been hypothesized as an endophenotype for autism. In this study we used twin modelling to assess the role of genetics in basic measures of visual disengagement, and tested their putative association to autistic traits in the general population. We used the Gap Overlap task in a sample of 492 twins. Results showed that most…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders)
Cohen-Gilbert, Julia E.; Stein, Elena R.; Gunnar, Megan R.; Thomas, Kathleen M. – Journal of Early Adolescence, 2018
This study investigated whether brain-derived neurotrophic factor (BDNF) genotype moderated inhibitory control during an emotionally valenced task in a sample of internationally adopted adolescents (N = 109, ages 12-13 years) who spent their early years in institutional care. Participants were genotyped for the Val66Met polymorphism of the BDNF…
Descriptors: Stress Variables, Genetics, Inhibition, Task Analysis
Bostelmann, M.; Glaser, B.; Zaharia, A.; Eliez, S.; Schneider, M. – Journal of Intellectual Disability Research, 2017
Background: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is a genetic syndrome characterised by a unique cognitive profile. Individuals with the syndrome present several non-verbal deficits, including visual memory impairments and atypical exploration of visual information. In this study, we seek to understand how visual attention may…
Descriptors: Visual Impairments, Retention (Psychology), Multiple Choice Tests, Genetics
Galli, Manuela; Cimolin, Veronica; Vismara, Luca; Grugni, Graziano; Camerota, Filippo; Celletti, Claudia; Albertini, Giorgio; Rigoldi, Chiara; Capodaglio, Paolo – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
Prader-Willi syndrome (PWS) and Ehlers-Danlos syndrome (EDS) are two different genetical disorders both characterized, among other features, by muscular hypotonia. Postural control seems to be impaired in both conditions. The aim of the present study was to quantitatively compare postural control in adult PWS and EDS using stabilometric platform…
Descriptors: Visual Perception, Patients, Muscular Strength, Mental Retardation
Belmonte, Matthew K.; Gomot, Marie; Baron-Cohen, Simon – Journal of Child Psychology and Psychiatry, 2010
Background: In addition to their more clinically evident abnormalities of social cognition, people with autism spectrum conditions (ASC) manifest perturbations of attention and sensory perception which may offer insights into the underlying neural abnormalities. Similar autistic traits in ASC relatives without a diagnosis suggest a continuity…
Descriptors: Autism, Pervasive Developmental Disorders, Attention, Physiology
