Synaptically released Zn[superscript 2+] is a potential modulator of neurotransmission and synaptic plasticity in fear-conditioning pathways. Zinc transporter 3 (ZnT3) knock-out (KO) mice are well suited to test the role of zinc in learned fear, because ZnT3 is colocalized with synaptic zinc, responsible for its transport to synaptic vesicles,…

Remembering events frequently involves associating objects and their associated locations in space, and it has been implicated that the areas associated with the hippocampus are important in this function. The current study examined the role of the perirhinal cortex in retrieving familiar object-place paired associates, as well as in acquiring…

Despite the importance of semantic relationships to our understanding of semantic knowledge, the nature of the neural processes underlying these abilities are not well understood. In order to investigate these processes, 20 healthy adults listened to thematically related (e.g., leash-dog), taxonomically related (e.g., horse-dog), or unrelated…

This study examined how the two cerebral hemispheres recruit semantic processing mechanisms by combining event-related potential measures and visual half-field methods in a word priming paradigm in which semantic strength and predictability were manipulated using lexically associated word pairs. Activation patterns on the late positive complex…

Researchers of metacognitive development in adulthood have exclusively used extreme-age-groups designs. We used a full cross-sectional sample (N = 285, age range: 18-80) to evaluate how associative relatedness and encoding strategies influence judgments of learning (JOLs) in adulthood. Participants studied related and unrelated word pairs and made…

Perruchet, Cleeremans, and Destrebecqz (2006) reported a striking dissociation between trends in the conscious expectancy of an event and the speed of a response that is cued by that event. They argued that this indicates the operation of independent processes in human associative learning. However, there remains a strong possibility that this…

One likely mechanism in learning new skills is change in synchronous connections between distributed neural networks, which can be measured by coherence analysis of electroencephalographic patterns. This study examined coherence changes during the learning of two tasks, a word association task and a figure association task. Although learning…

Developing morphological awareness (MA) is an essential component of vocabulary growth, given that it can contribute to enhanced depth of vocabulary knowledge and provides a pathway to deeper associations with more members of a word family. Despite the considerable body of vocabulary research, specific relationships between different aspects of MA…

Two lexical decision experiments examined the joint effects of stimulus quality, semantic context, and cue-target associative strength when all factors were intermixed in a block of trials. Both experiments found a three-way interaction. Semantic context and stimulus quality interacted when associative strength between cue-target pairs was strong,…

Word association responses in first-language (L1) Spanish and second-language (L2) English were investigated by means of response latencies and types of associative response produced. The primary aims were to establish whether (a) some response types are produced more often or faster than others, (b) participants' L2 response time profiles mirror…

Infants at 1;2 demonstrate difficulty in accessing subtle phonetic information about newly learned word-object pairings (Stager & Werker, 1997). In this study, we examined whether or not infants can access subtle prosodic information such as lexical stress in a word learning task. We tested infants younger than 1;2 to see if they could learn two…

Recent evidence demonstrated that dopamine within the nucleus accumbens mediates consolidation of both associative and nonassociative memories. However, the specific contribution of the nucleus accumbens subregions, core and shell, and of D1 and D2 receptors subtypes has not been yet clarified. The aim of this study was, therefore, to directly…

Our environment contains regularities distributed in space and time that can be detected by way of statistical learning. This unsupervised learning occurs without intent or awareness, but little is known about how it relates to other types of learning, how it affects perceptual processing, and how quickly it can occur. Here we use fMRI during…

Recent evidence suggests the existence of multiple cognitive mechanisms that support the general cognitive ability factor (g). Working memory and processing speed are the two best established candidate mechanisms. Relatively little attention has been given to the possibility that associative learning is an additional mechanism contributing to g.…

The effects of associative strength and gist relations on rates of children's and adults' true and false memories were examined in three experiments. Children aged 5-11 and university-aged adults participated in a standard Deese/Roediger-McDermott false memory task using DRM and category lists in two experiments and in the third, children…