Psychometric Properties of the Scale of Positive and Negative Experience (SPANE) have been extensively evaluated in numerous countries, but not in Indonesia. This study investigated factor structure, reliability, measurement invariance, and validity of SPANE scores among a sample of Indonesian university students (N = 405). Multiple measurement models, including one-factor and two-factor models, were tested. The results supported a correlated two-factor structure, with the uniqueness of general and specific items allowed to correlate with each other. The SPANE scores indicated acceptable internal consistency reliability for the sample in this study. Measurement invariance analyses indicated that the two-factor structure was invariant across sex. Furthermore, the SPANE scores correlated with life satisfaction in the expected direction: Positive feelings showed a positive correlation with life satisfaction, while negative feelings showed a negative correlation. With its conciseness, the SPANE shows promising results, though future research on its invariance across different population subgroups is needed.