Presents a case study on the story of Dr. Frances Kelsey and the drug thalidomide, which was widely used in Europe for its therapeutic effects in the 1960s and later identified as having multiple effects on the body during development by the Food and Drug Administration (FDA). Describes the drug approval process in the United States and…

Understanding natural and human-induced hazards is an important part of the standards-based science curriculum. Experience, however, indicates that the topic is a difficult one for many students. We have developed an exciting investigative laboratory exercise that uses simulated food-based case studies to promote critical thinking and improve…

Presents an experiment that demonstrates that common substances, whether or not the students think of them as medicines, drugs of abuse, or foods, have toxic effects on Daphnia. Combines an inexpensive hands-on experiment with extensive discussion to help the students think about chemical concentration, potency, and the difference between harmful…

Introduces a brine shrimp assay to demonstrate the effects of the biological activity of herbal remedies. Describes two protocols, one using aqueous extracts and the other using methanol extracts. (Contains 21 references.) (YDS)

Article tells the story of how a New York City customs man was bit by a King Cobra from Thailand and the medical treatment he received. Describes three types of snake venoms: hemotoxins, cytotoxins, and neurotoxins. Explains how horses are used to produce antitoxins and side effects of the antitoxins on humans. (PR)

The cumulative result of almost 100 years of mining, milling, and smelting has left areas of Jasper County, Missouri, contaminated with high levels of the trace metals Pb, Cd, and Zn. The site was listed on the National Priorities List in 1990 and is now known as the Jasper County or Oronogo-Duenweg Mining Belt Superfund Site. The U.S.…

Describes a microbial bioassay, using molds as test organisms, that demonstrates toxicities of environmental pollutants. Includes laboratory methods and applications for the experiment. (MDH)

Introduces the Environmental Inquiry (EI) program which focuses on five topics: watershed dynamics, environmental toxicology, ecology of invasive species, biodegradations, and urban ecosystem modeling. (YDS)

This curriculum consists of a one-week course of study designed to introduce K-3 students to (or increase their awareness of) toxic substances commonly found in the home. It includes an introduction/conceptual framework and four learning activities for four concept areas (and an optional word puzzle). Each activity includes a statement of purpose,…

Describes a simple emulsification test and germination test used to determine the cleaning power and toxicity of three different household cleaning agents. (MKR)

Lead (Pb) is one of the most significant environmental contaminants worldwide and has significant human health effects. Historic use of Pb in paint and gasoline, in particular, have made this contaminant ubiquitous in our environment although widespread use of Pb has declined in the USA. Unfortunately, segments of the population are still…

This curriculum consists of a one-week course of study designed to introduce students in grades 4-6 to (or increase their awareness of) toxic substances commonly found in the home. It includes an introduction/conceptual framework, four lessons, a unit evaluation, and appendices. Each lesson consists of a statement of purpose, objectives,…

This curriculum consists of a one-week course of study designed to introduce students in grades 7-8 to (or increase their awareness of) toxic substances commonly found in the home. It includes an introduction/conceptual framework, four lessons, a unit test, and appendices. Each lesson consists of a statement of purpose, objectives,…

This book is designed for middle school earth science teachers to help their students learn about problems with toxic leaking and scientific literacy through event-based science. Unlike traditional curricula, the event-based earth science module is a student-centered, interdisciplinary, inquiry-oriented program that emphasizes cooperative…

Presented are activities suggested through Project L.A.B.S. that involve the topic of toxicology. Activities include suggested research, the risk benefit seesaw, human-made compounds, legislation, a historical perspective, and health. A suggested readings list is provided. (KR)