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Head Circumferences in Twins with and without Autism Spectrum Disorders
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Froehlich, Wendy; Cleveland, Sue; Torres, Andrea; Phillips, Jennifer; Cohen, Brianne; Torigoe, Tiffany; Miller, Janet; Fedele, Angie; Collins, Jack; Smith, Karen; Lotspeich, Linda; Croen, Lisa A.; Ozonoff, Sally; Lajonchere, Clara; Grether, Judith K.; Hallmayer, Joachim – Journal of Autism and Developmental Disorders, 2013
To determine the genetic relationship between head circumference (HC) and Autism Spectrum Disorders (ASDs). Twin pairs with at least one twin with an ASD were assessed. HCs in affected and unaffected individuals were compared, as were HC correlations in monozygotic and dizygotic pairs. 404 subjects, ages 4-18, were included. 20% of males and 27%…
Descriptors: Twins, Autism, Pervasive Developmental Disorders, Physical Characteristics
Motor Impulsivity during Childhood and Adolescence: A Longitudinal Biometric Analysis of the Go/No-Go Task in 9- to 18-Year-Old Twins
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Bezdjian, Serena; Tuvblad, Catherine; Wang, Pan; Raine, Adrian; Baker, Laura A. – Developmental Psychology, 2014
In the present study, we investigated genetic and environmental effects on motor impulsivity from childhood to late adolescence using a longitudinal sample of twins from ages 9 to 18 years. Motor impulsivity was assessed using errors of commission (no-go errors) in a visual go/no-go task at 4 time points: ages 9-10, 11-13, 14-15, and 16-18 years.…
Descriptors: Genetics, Environmental Influences, Twins, Children
Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder
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Neale, Benjamin M.; Medland, Sarah E.; Ripke, Stephan; Asherson, Philip; Franke, Barbara; Lesch, Klaus-Peter; Faraone, Stephen V.; Nguyen, Thuy Trang; Schafer, Helmut; Holmans, Peter; Daly, Mark; Steinhausen, Hans-Christoph; Freitag, Christine; Reif, Andreas; Renner, Tobias J.; Romanos, Marcel; Romanos, Jasmin; Walitza, Susanne; Warnke, Andreas; Meyer, Jobst; Palmason, Haukur; Buitelaar, Jan; Vasquez, Alejandro Arias; Lambregts-Rommelse, Nanda; Gill, Michael; Anney, Richard J. L.; Langely, Kate; O'Donovan, Michael; Williams, Nigel; Owen, Michael; Thapar, Anita; Kent, Lindsey; Sergeant, Joseph; Roeyers, Herbert; Mick, Eric; Biederman, Joseph; Doyle, Alysa; Smalley, Susan; Loo, Sandra; Hakonarson, Hakon; Elia, Josephine; Todorov, Alexandre; Miranda, Ana; Mulas, Fernando; Ebstein, Richard P.; Rothenberger, Aribert; Banaschewski, Tobias; Oades, Robert D.; Sonuga-Barke, Edmund; McGough, James; Nisenbaum, Laura; Middleton, Frank; Hu, Xiaolan; Nelson, Stan – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of…
Descriptors: Attention Deficit Hyperactivity Disorder, Hospitals, Association Measures, Genetics
Descriptive Epidemiology of Autism in a California Population: Who Is at Risk?
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Croen, Lisa A.; Grether, Judith K.; Hoogstrate, Jenny; Selvin, Steve – Journal of Autism and Developmental Disorders, 2002
This study investigated associations between selected infant and maternal characteristics and autism risk in 4381 California children with autism. Increased risk factors were observed for males, multiple births, and children born to black mothers. Risk increased as maternal age and maternal education increased. Children of immigrant mothers had…
Descriptors: Age Differences, Autism, Blacks, Demography
Twinshock: Twins Are a Hard Happiness. Issues in the Care of Multiple Birth Children.
Malmstrom, Patricia M.; And Others – 1987
The multiple-birth family must struggle to cope with extraordinary issues with little or no information or support, and with little understanding from the community at large. This paper describes such issues and their impact on the lives of families of twins, triplets, quadruplets, and quintuplets from conception through adolescence. An…
Descriptors: Adolescents, Child Rearing, Cultural Influences, Developmental Stages