Owing to the critical role of stereochemistry in biotechnology, medicine, and industry, it must be well represented in undergraduate lab curricula. To achieve these stereochemical laboratory requirements without sacrificing existing lab techniques, we modified two standard laboratory experiments to include chiral GC analysis as follows. (1) The…

The pharmaceutical and medicine manufacturing industry has become the largest industrial sector for the employment of chemists, indicating a need for experiments with a pharmaceutical sciences context in the undergraduate chemistry curriculum. In the pharmaceutical industry, testing drug dissolution is a key analytical task for solid oral dosage…

Chemists have always designed and deployed cross-disciplinary approaches that interface chemistry with other disciplines to proffer solutions to many human problems. We designed a laboratory experiment that implements chemistry concepts in a biological model to prime undergraduate students to appreciate interdisciplinarity as an approach to…

The essential component of expanding an undergraduate curriculum is the inclusion of lab experiments in nanoscience and nanomaterials, which significantly impact health and the environment through their use in food, cosmetics, agriculture, and medicine. We designed a laboratory experiment based on the atomic force microscopy (AFM) analysis of the…

A comprehensive chemistry laboratory experiment, including the synthesis of Pt/Al[subscript 2]O[subscript 3] catalysts at different conditions, structure characterization, and the real-world application exploration, has been designed for upper-division undergraduate and graduate students as an expansion and improvement of the professional…

Removing the pollutants from various wastewater is crucial to the environment, ecology, and humans. However, the pollutants are generally removed by chemical decomposition, which not only consumes a lot of energy but also produces carbon emissions. Electrochemical flocculation is effective to extract pollutant molecules and heavy ions from…

Heterocyclic compounds are an integral part of research, particularly in the pharmaceutical field. The synthesis of such compounds in an undergraduate laboratory can help students understand the relevance and importance of their field of study. Our experimental activity introduces a novel procedure to synthesize coumarin, a heterocyclic formed by…

Calculating analytical uncertainties as a part of method validation is a relevant aspect of field and laboratory practices in instrumental analytical chemistry subjects, which usually require complex algorithms. This work describes the development and didactic use of an automatic and straightforward informatics tool, implemented in an Excel macro,…

We report the design of a low-cost electrochemical workstation and open-source graphical user interface capable of performing a variety of electrochemical methods in an undergraduate teaching laboratory. The instrument--based on the popular Arduino microcontroller board--can be constructed from common components for $40 USD. The modular design of…

A one-pot multicomponent synthesis of unsymmetrical indole-substituted methane derivative based on two consecutive reactions of p-methylbenzaldehyde with N-methylindole and 5,5-dimethyl-1,3-cyclohexanedione is described as an experiment that was carried out by second-year undergraduate chemistry students individually in a laboratory classroom. The…

S[subscript N]2 reactions are of fundamental importance in introductory organic chemistry courses, and a number of experiments suitable for the first-semester undergraduate organic lab have been previously reported. Most of these experiments have used alkyl halides as electrophiles, but alkyl halides are often less than ideal for reasons of…

We describe an experiment in which students use research-grade instrumentation to collect gas adsorption data in triplicate in a single 3 h laboratory period. The experiment reinforces the thermodynamic concepts taught in upper level physical chemistry courses and hands-on experience with instrumentation used in research laboratories. The speed of…

Heterocycles, more specifically those containing nitrogen, make up a family of molecules with great pharmaceutical potential. Many approved drugs, notably anticancer drugs, contain a nitrogen-based heterocycle. To expose students to this class of molecules, we used the Paal--Knorr reaction for the synthesis of edaravone, a pyrazolone derivative.…

An undergraduate laboratory experiment for the synthesis of biologically significant bis-4-hydroxycoumarins using a new catalyst is described here. An experimental setup plan, monitoring the reaction by TLC, isolation of the product, safe laboratory handling procedures, and significance of data reproducibility of the result are the main learning…

The goal of this laboratory exercise is to give upper-level undergraduate students an introduction to sterile technique in mammalian cell culture and metabolism. The experiment can be completed within a 3-h lab period and can be performed either in conjunction with other biochemistry/metabolism experiments or used as a stand-alone experiment. In…