This article responds to the question: In what ways can an international research partnership involving partners from Canada and Ghana contribute to efforts to foster inclusive education in schools? We describe a research partnership that involved universities in Canada and Ghana, civil-society organizations, schools, and government departments. We examine opportunities and learning experiences that were facilitated by the partnership. Key lessons from the partnership are articulated. A framework is proposed, the 4R Model for International Research Partnership that prioritizes reciprocity, responsiveness, relationships, and resources to ensure that international research partnerships are best positioned to accomplish their goals.