The internationalization of universities has become increasingly important in recent decades. A dominant internationalization model, influenced by principles of new public management, has emerged. Latin American universities have undergone significant changes as a result of this trend. This paper takes inspiration from the sociology of translation to examine how leading Latin American institutions are addressing these challenges at both organizational and cultural levels. The findings indicate that cultural transformation is prevalent, strongly influenced by the Latin American tradition of extension. However, at the organizational level, imitation is more relevant, as evidenced by the adoption of new public management principles to devise strategies, plans, and programs that prioritize professionalization and the widespread use of indicators. This development gives rise to a distinct cultural internationalization model for Latin American universities.