A method for the synthesis of flufenamic acid, a nonstereoidal anti-inflammatory drug (NSAID) of the anthranilate family (fenams), is described as an experiment for the upper-division undergraduate organic chemistry laboratory. The key step is the formation of the diarylamine moiety of flufenamic acid by a novel reaction consisting of the coupling…

Dispersion forces are ubiquitous in chemistry, yet they are often misunderstood. This article provides background into why they are called dispersion forces and explains how to describe them in terms of time-independent quantum mechanics. The article also describes the breakdown of the multipole series that is often used to describe dispersion…

This paper describes a simple and effective trick with a ball on a flat surface. The trick does not require any skills, is surprising and can provide an attention-grabbing, fun introduction for high school students into the topic of pure rolling motion versus rolling with slipping.

Protein engineering represents a modern approach to generate novel proteins for the different fields of biotechnology. Here, we report about an 8-day laboratory activity in which students generate enzyme variants to degrade the herbicide glyphosate. The students conduct a true research experiment in an important field (bioremediation by novel,…

Analysis of collisions is standardly included in the introductory physics course. In one dimension (1D), there do not seem to be any unusual issues: Typically, the initial velocities of the two colliding objects are specified, and the problem is to find the final velocities. In 1D there are therefore two unknown variables. One can write the…

In recent years, smartphone sensors have been frequently used in educational demonstrations to improve students' understanding of certain physical kinematic topics. In particular, the sensors on modern smartphones enable students to use their phones as physics mini-laboratories, and they have been used to analyze objects' speeds and accelerations…

A central theme in introductory and advanced chemical education courses pertains directly to the transfer of electrons between atoms, ions, or molecules. This article presents theoretical treatments of electron transfer with specific attention toward applying these principles to experiment. The goal is to revitalize teaching electron transfer at…

X-ray fluorescence is subject to significant matrix effects, which must be corrected in order to obtain accurate quantitative results. These are due to both absorption and enhancement effects, which are a consequence of the fact that both the analyte and the matrix absorb and fluoresce in the X-ray region, and this affects the magnitude of the…

A "map" is presented to describe the different stereochemical relationships among carbohydrates, in both the hexose and pentose series. When implemented, it allows chemistry students, teachers, and researchers to readily identify different sugars' stereochemical interconnections. It may also help orient chemists toward retrosyntheses, in…

This work seeks to add to the growing body of chemistry education research that emphasizes the teaching and learning of advanced topics, focusing on students' understanding of enzyme kinetics. The data corpus relevant to this study involved 14 second-year undergraduate students enrolled in an introductory biochemistry course taught in a chemistry…

Although kinetics forms a foundational part of the chemical curriculum, laboratory experiences with the subject are often limited and lack relevance to the actual practice of chemistry. Presented is an inquiry-based lab focused on Michaelis-Menten kinetics, implemented in an upper-level, university physical chemistry laboratory. Student learning…

The conical pendulum is a topic theoretically approached in physics literature, but with little experimental activity developed due to the difficulty of reproducing the conical motion in ideal experimental conditions. This work consisted of studying the motion of a rigid conical pendulum using video analysis. The experimental results were used as…

Overall, the major chemical information retrieval products Reaxys and SciFinder have several similarities such as numbers of document records, numbers of characterized substances (counting the PubChem Compounds integrated in Reaxys), and, possibly, numbers of different chemical reactions. Reaxys has well over 100 times the number of experimental…

The Leidenfrost nanochemistry synthesis of gold colloids was introduced in this "Journal" as an advanced method to synthesize gold nanoparticles during an undergraduate nanochemistry research project. When trying to repeat these experiments in the laboratory, we experienced difficulties in the synthesis of the gold nanoparticles since…

Numerous previous studies have reported the difficulties associated with learning the Brønsted-Lowry acid-base model. The Brønsted-Lowry acid-base model requires complex systems thinking because it considers random interactions between reactant and product particles and effective particle collisions in forward and reverse reactions. The system…